Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 145586..146129 | Replicon | plasmid 24 |
| Accession | NZ_LR134433 | ||
| Organism | Legionella adelaidensis strain NCTC12735 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A0W0R3S2 |
| Locus tag | EL206_RS08100 | Protein ID | WP_058461425.1 |
| Coordinates | 145586..145876 (-) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A0W0R3T3 |
| Locus tag | EL206_RS08105 | Protein ID | WP_058461426.1 |
| Coordinates | 145866..146129 (-) | Length | 88 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL206_RS08090 | 141443..143014 | + | 1572 | WP_058461424.1 | pyridoxal phosphate-dependent aminotransferase | - |
| EL206_RS08095 | 143074..145149 | + | 2076 | WP_065310920.1 | PAS domain-containing hybrid sensor histidine kinase/response regulator | - |
| EL206_RS08100 | 145586..145876 | - | 291 | WP_058461425.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| EL206_RS08105 | 145866..146129 | - | 264 | WP_058461426.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| EL206_RS08110 | 146374..146910 | + | 537 | WP_058461427.1 | hypothetical protein | - |
| EL206_RS08115 | 146971..147489 | - | 519 | WP_058461428.1 | AAA family ATPase | - |
| EL206_RS08120 | 147670..148005 | + | 336 | WP_058461429.1 | tRNA-binding protein | - |
| EL206_RS08125 | 148195..149883 | + | 1689 | WP_058461430.1 | Kef family K(+) transporter | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..365419 | 365419 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 14294.15 Da Isoelectric Point: 5.5500
>T287876 WP_058461425.1 NZ_LR134433:c145876-145586 [Legionella adelaidensis]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFF
Download Length: 291 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0W0R3S2 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0W0R3T3 |