287876

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 145586..146129 Replicon plasmid 24
Accession NZ_LR134433
Organism Legionella adelaidensis strain NCTC12735

Toxin (Protein)


Gene name relE Uniprot ID A0A0W0R3S2
Locus tag EL206_RS08100 Protein ID WP_058461425.1
Coordinates 145586..145876 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0W0R3T3
Locus tag EL206_RS08105 Protein ID WP_058461426.1
Coordinates 145866..146129 (-) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL206_RS08090 141443..143014 + 1572 WP_058461424.1 pyridoxal phosphate-dependent aminotransferase -
EL206_RS08095 143074..145149 + 2076 WP_065310920.1 PAS domain-containing hybrid sensor histidine kinase/response regulator -
EL206_RS08100 145586..145876 - 291 WP_058461425.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL206_RS08105 145866..146129 - 264 WP_058461426.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EL206_RS08110 146374..146910 + 537 WP_058461427.1 hypothetical protein -
EL206_RS08115 146971..147489 - 519 WP_058461428.1 AAA family ATPase -
EL206_RS08120 147670..148005 + 336 WP_058461429.1 tRNA-binding protein -
EL206_RS08125 148195..149883 + 1689 WP_058461430.1 Kef family K(+) transporter -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..365419 365419


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 14294.15 Da        Isoelectric Point: 5.5500

>T287876 WP_058461425.1 NZ_LR134433:c145876-145586 [Legionella adelaidensis]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFF

Download         Length: 291 bp


Antitoxin


Download         Length: 88 a.a.        Molecular weight: 12969.56 Da        Isoelectric Point: 5.5500

>AT287876 WP_058461426.1 NZ_LR134433:c146129-145866 [Legionella adelaidensis]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFF

Download         Length: 264 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0W0R3S2


Antitoxin

Source ID Structure
AlphaFold DB A0A0W0R3T3

References