Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2800866..2801373 Replicon chromosome
Accession NZ_LR134406
Organism Arachnia propionica strain NCTC12967

Toxin (Protein)


Gene name relE Uniprot ID A0A3S4Y8S1
Locus tag EL272_RS12590 Protein ID WP_061788152.1
Coordinates 2800866..2801120 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A3N4D924
Locus tag EL272_RS12595 Protein ID WP_014847591.1
Coordinates 2801122..2801373 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL272_RS12565 2797087..2797560 - 474 WP_014847587.1 GNAT family N-acetyltransferase -
EL272_RS12570 2797665..2799068 - 1404 WP_159424568.1 DHA2 family efflux MFS transporter permease subunit -
EL272_RS12575 2799137..2799961 + 825 WP_061788150.1 class I SAM-dependent methyltransferase -
EL272_RS12585 2800526..2800807 + 282 WP_126409458.1 hypothetical protein -
EL272_RS12590 2800866..2801120 - 255 WP_061788152.1 Txe/YoeB family addiction module toxin Toxin
EL272_RS12595 2801122..2801373 - 252 WP_014847591.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EL272_RS12600 2801551..2802135 - 585 WP_014847592.1 TetR family transcriptional regulator -
EL272_RS12605 2802206..2803435 + 1230 WP_061788153.1 MFS transporter -
EL272_RS12610 2803422..2804375 - 954 WP_014847594.1 NmrA/HSCARG family protein -
EL272_RS12615 2804497..2804880 + 384 WP_014847595.1 helix-turn-helix transcriptional regulator -
EL272_RS12620 2804956..2805990 + 1035 WP_061788154.1 DUF2330 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9762.01 Da        Isoelectric Point: 6.4548

>T287870 WP_061788152.1 NZ_LR134406:c2801120-2800866 [Arachnia propionica]
VRLAWDPSAWEDYTYWQAADSRILKRINALIDTCLRDPSGGIGKPEQLRYGAPGAWSRRITEEHRLVYLVDGDDLVILQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9497.50 Da        Isoelectric Point: 4.6794

>AT287870 WP_014847591.1 NZ_LR134406:c2801373-2801122 [Arachnia propionica]
VSISASEARRTLFPLIEQVNDDRTAVEIVSRKGNAVLMSADEYAAWQETAYLFRSPANARRLLDAYERAREGRSEEHDLI
RED

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S4Y8S1

Antitoxin

Source ID Structure
AlphaFold DB A0A3N4D924

References