Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3615480..3616017 Replicon chromosome
Accession NZ_LR134396
Organism Providencia rustigianii strain NCTC8113

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL244_RS16610 Protein ID WP_112837460.1
Coordinates 3615480..3615773 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A379G845
Locus tag EL244_RS16615 Protein ID WP_039854881.1
Coordinates 3615763..3616017 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL244_RS16580 3611086..3612402 - 1317 WP_126462384.1 N-acetylmuramoyl-L-alanine amidase AmiB -
EL244_RS16585 3612417..3612881 - 465 WP_006814566.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
EL244_RS16590 3613097..3614254 + 1158 WP_126462387.1 tRNA epoxyqueuosine(34) reductase QueG -
EL244_RS16610 3615480..3615773 - 294 WP_112837460.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL244_RS16615 3615763..3616017 - 255 WP_039854881.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL244_RS16620 3616106..3616648 - 543 WP_006814571.1 oligoribonuclease -
EL244_RS16625 3616786..3617838 + 1053 WP_006814572.1 small ribosomal subunit biogenesis GTPase RsgA -
EL244_RS16630 3617982..3618872 + 891 WP_006814573.1 phosphatidylserine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-75)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11286.16 Da        Isoelectric Point: 10.4251

>T287863 WP_112837460.1 NZ_LR134396:c3615773-3615480 [Providencia rustigianii]
MIYSIEFDERALKEWKKLDSSIRDQFKNKLKKLQKNPHVESARLHGELSSCYKIKLRSSGYRLVYQVIHSEIVIFVIAIG
KREASTAYTAANTRLVK

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9702.24 Da        Isoelectric Point: 6.3653

>AT287863 WP_039854881.1 NZ_LR134396:c3616017-3615763 [Providencia rustigianii]
MTTIQIRVDEQLKKEAFQAFEKLNLSPSDALRLFLRYVAENKKLPFTEVSVVVSESDADDEILAVVRERLKKPAKRIRVN
LDDI

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A379G845

References