Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3615480..3616017 Replicon chromosome
Accession NZ_LR134396
Organism Providencia rustigianii strain NCTC8113

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL244_RS16610 Protein ID WP_112837460.1
Coordinates 3615480..3615773 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A379G845
Locus tag EL244_RS16615 Protein ID WP_039854881.1
Coordinates 3615763..3616017 (-) Length 85 a.a.

Genomic Context

EL244_RS16590EL244_RS16625EL244_RS16630EL244_RS16580EL244_RS16585EL244_RS16610EL244_RS16615EL244_RS16620
Location: 3613097..3614254 (1158 bp)
Type: Others
Protein ID: WP_126462387.1
Location: 3616786..3617838 (1053 bp)
Type: Others
Protein ID: WP_006814572.1
Location: 3617982..3618872 (891 bp)
Type: Others
Protein ID: WP_006814573.1
Location: 3611086..3612402 (1317 bp)
Type: Others
Protein ID: WP_126462384.1
Location: 3612417..3612881 (465 bp)
Type: Others
Protein ID: WP_006814566.1
Location: 3615480..3615773 (294 bp)
Type: Toxin
Protein ID: WP_112837460.1
Location: 3615763..3616017 (255 bp)
Type: Antitoxin
Protein ID: WP_039854881.1
Location: 3616106..3616648 (543 bp)
Type: Others
Protein ID: WP_006814571.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL244_RS165803611086..3612402-1317WP_126462384.1N-acetylmuramoyl-L-alanine amidase AmiB-
EL244_RS165853612417..3612881-465WP_006814566.1tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE-
EL244_RS165903613097..3614254+1158WP_126462387.1tRNA epoxyqueuosine(34) reductase QueG-
EL244_RS166103615480..3615773-294WP_112837460.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EL244_RS166153615763..3616017-255WP_039854881.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
EL244_RS166203616106..3616648-543WP_006814571.1oligoribonuclease-
EL244_RS166253616786..3617838+1053WP_006814572.1small ribosomal subunit biogenesis GTPase RsgA-
EL244_RS166303617982..3618872+891WP_006814573.1phosphatidylserine decarboxylase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-75)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11286.16 Da        Isoelectric Point: 10.4251

>T287863 WP_112837460.1 NZ_LR134396:c3615773-3615480 [Providencia rustigianii]
MIYSIEFDERALKEWKKLDSSIRDQFKNKLKKLQKNPHVESARLHGELSSCYKIKLRSSGYRLVYQVIHSEIVIFVIAIG
KREASTAYTAANTRLVK

Download         Length: 294 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9702.24 Da        Isoelectric Point: 6.3653

>AT287863 WP_039854881.1 NZ_LR134396:c3616017-3615763 [Providencia rustigianii]
MTTIQIRVDEQLKKEAFQAFEKLNLSPSDALRLFLRYVAENKKLPFTEVSVVVSESDADDEILAVVRERLKKPAKRIRVN
LDDI

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A379G845

References