Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) NpoTA/ParE(toxin)
Location 2930878..2931920 Replicon chromosome
Accession NZ_LR134383
Organism Legionella jordanis strain NCTC11533

Toxin (Protein)


Gene name NpoT Uniprot ID -
Locus tag EL203_RS14470 Protein ID WP_058472256.1
Coordinates 2930878..2931036 (-) Length 53 a.a.

Antitoxin (Protein)


Gene name NpoA Uniprot ID A0A0W0VD64
Locus tag EL203_RS13265 Protein ID WP_058471765.1
Coordinates 2931057..2931920 (-) Length 288 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL203_RS13230 2926301..2926579 - 279 WP_058471771.1 hypothetical protein -
EL203_RS13235 2926852..2927109 + 258 WP_058471770.1 hypothetical protein -
EL203_RS13240 2927154..2927396 - 243 WP_058471769.1 hypothetical protein -
EL203_RS13245 2927528..2927686 + 159 WP_197723118.1 DUF3309 domain-containing protein -
EL203_RS13250 2927728..2928576 - 849 WP_058471768.1 class II glutamine amidotransferase -
EL203_RS13255 2928644..2929936 - 1293 WP_058471767.1 MFS transporter -
EL203_RS13260 2930096..2930848 + 753 WP_058471766.1 endonuclease/exonuclease/phosphatase family protein -
EL203_RS14470 2930878..2931036 - 159 WP_058472256.1 hypothetical protein Toxin
EL203_RS13265 2931057..2931920 - 864 WP_058471765.1 SDR family oxidoreductase Antitoxin
EL203_RS13270 2931973..2932329 - 357 WP_058471764.1 PRC-barrel domain-containing protein -
EL203_RS13275 2932341..2933024 - 684 WP_058471763.1 BON domain-containing protein -
EL203_RS13280 2933412..2934272 + 861 WP_058471762.1 Ku protein -
EL203_RS13285 2934637..2936919 + 2283 WP_058471761.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 53 a.a.        Molecular weight: 6042.70 Da        Isoelectric Point: 10.3195

>T287845 WP_058472256.1 NZ_LR134383:c2931036-2930878 [Legionella jordanis]
MAQGDKSKYTDKQKRKAHHIEEHYRDKGVSKQEAEKRAWATVNEQDKGGKKS

Download         Length: 159 bp

Antitoxin


Download         Length: 288 a.a.        Molecular weight: 31252.39 Da        Isoelectric Point: 5.5832

>AT287845 WP_058471765.1 NZ_LR134383:c2931920-2931057 [Legionella jordanis]
MPHGKQQQPPQHQAKQPGIEAFMHPKPEYISPQYKGSDKLLGKKALITGGDSGIGRAVACAFALEGADVVIQYLNTEQQD
AEETKEFIENAGRKCWLLPSPLDSYEVCEQLVKRALEACSHINILVNNAAEQHPKGSVDEISPEQLEQTFRTNFFAYFYM
VKSLLPHMEKGDVIINTTSVTAYKGSEHLIDYSATKGAILAFTRSLSQNLISKGIRVNGVAPGPIWTPLIPASFTADEVE
EFGSQVPMSRAGQPSEVAPSYVFLASADSSYMTGQVLHPNGGVIVNS

Download         Length: 864 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0VD64

References