287842

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 565212..565768 Replicon chromosome
Accession NZ_LR134382
Organism Bordetella hinzii strain NCTC13199

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag EL326_RS02795 Protein ID WP_032978872.1
Coordinates 565478..565768 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL326_RS02790 Protein ID WP_032957511.1
Coordinates 565212..565490 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL326_RS02765 561899..563107 + 1209 WP_032957508.1 site-specific integrase -
EL326_RS02770 563195..563365 + 171 Protein_541 AlpA family phage regulatory protein -
EL326_RS02775 563368..563703 + 336 Protein_542 AAA family ATPase -
EL326_RS24040 563735..563905 - 171 WP_155271649.1 hypothetical protein -
EL326_RS02780 563902..564633 - 732 WP_032978894.1 recombinase family protein -
EL326_RS02785 564756..565007 - 252 WP_032978869.1 hypothetical protein -
EL326_RS02790 565212..565490 + 279 WP_032957511.1 CopG family ribbon-helix-helix protein Antitoxin
EL326_RS02795 565478..565768 + 291 WP_032978872.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL326_RS02800 565769..566029 + 261 WP_032978875.1 hypothetical protein -
EL326_RS02805 566041..566499 + 459 WP_080700866.1 helix-turn-helix domain-containing protein -
EL326_RS02810 566725..567507 + 783 WP_032978897.1 DUF1837 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 563735..574690 10955
- inside Genomic island - - 561899..573903 12004


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10900.56 Da        Isoelectric Point: 9.5041

>T287842 WP_032978872.1 NZ_LR134382:565478-565768 [Bordetella hinzii]
VPRLIWTPPAVADVQRLYRFLAPKDADAAQRAVKAIRAGVKILAHQPRIGRPVEDMEPEFREWLIDFGNSGYVALYRFDG
ENIAILAVRHQKEAGY

Download         Length: 291 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10801.20 Da        Isoelectric Point: 6.0964

>AT287842 WP_032957511.1 NZ_LR134382:565212-565490 [Bordetella hinzii]
MARATSIKLDDELKGRVQHLAEARRRTSHWIMREAIAQYVEREEKREAFKQDALRAWEEYQRTGLHLTLEEADAWLAKLE
AGEDAELPKCHV

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References