Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 1793415..1794051 Replicon chromosome
Accession NZ_LR134378
Organism Lautropia mirabilis strain NCTC12852

Toxin (Protein)


Gene name shpA Uniprot ID A0A930GK54
Locus tag EL249_RS07275 Protein ID WP_040531190.1
Coordinates 1793761..1794051 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID E7RWV9
Locus tag EL249_RS07270 Protein ID WP_005673414.1
Coordinates 1793415..1793774 (-) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL249_RS13195 1790955..1791482 - 528 Protein_1421 hypothetical protein -
EL249_RS07260 1791654..1793033 + 1380 WP_083799483.1 YIP1 family protein -
EL249_RS07270 1793415..1793774 - 360 WP_005673414.1 BrnA antitoxin family protein Antitoxin
EL249_RS07275 1793761..1794051 - 291 WP_040531190.1 BrnT family toxin Toxin
EL249_RS07285 1795000..1795638 + 639 WP_005673410.1 hypothetical protein -
EL249_RS07290 1795794..1796165 + 372 WP_040531188.1 dihydroneopterin aldolase -
EL249_RS07295 1796138..1797805 - 1668 WP_005673408.1 ABC transporter substrate-binding protein -
EL249_RS07300 1798222..1798722 - 501 WP_005673405.1 dihydrofolate reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-89)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(10-93)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10999.47 Da        Isoelectric Point: 8.0496

>T287836 WP_040531190.1 NZ_LR134378:c1794051-1793761 [Lautropia mirabilis]
MRQRFTWDPAKAASNLRKHGISFEEAVCVFADPMAVTRQDRIENGEQRWQTIGAVGGFTLLLVAHTLWDDEAGIEVVRII
SARRADRKERRIYENG

Download         Length: 291 bp

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13352.00 Da        Isoelectric Point: 4.7420

>AT287836 WP_005673414.1 NZ_LR134378:c1793774-1793415 [Lautropia mirabilis]
MKTVSVTLDDLPPLSPERIAELRTLAERPDSEIDYSDIPAQDPADWADAERGRFYRPIKTQTSIRIDKDVMAWLKRDGKG
YQTRINAILREAMLRDLQQPATSQATPAAAQGERADANV

Download         Length: 360 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References