Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 412227..412704 Replicon chromosome
Accession NZ_LR134375
Organism Veillonella dispar strain NCTC11831

Toxin (Protein)


Gene name relE Uniprot ID C4FSP2
Locus tag EL171_RS01820 Protein ID WP_005387908.1
Coordinates 412438..412704 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C4FSP1
Locus tag EL171_RS01815 Protein ID WP_005387906.1
Coordinates 412227..412448 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL171_RS01800 408232..409689 + 1458 WP_005387899.1 hypothetical protein -
EL171_RS01805 409820..410338 + 519 WP_005387901.1 hypothetical protein -
EL171_RS01810 410379..411752 - 1374 WP_005387903.1 MFS transporter -
EL171_RS01815 412227..412448 + 222 WP_005387906.1 hypothetical protein Antitoxin
EL171_RS01820 412438..412704 + 267 WP_005387908.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL171_RS01825 412715..412927 + 213 WP_005387910.1 hypothetical protein -
EL171_RS01830 412994..414079 + 1086 WP_005387912.1 hypothetical protein -
EL171_RS01835 414153..414944 - 792 WP_005387914.1 carbon-nitrogen family hydrolase -
EL171_RS01845 415262..416065 + 804 WP_005387916.1 polysaccharide deacetylase family protein -
EL171_RS01850 416077..417015 + 939 WP_039969603.1 phosphodiester glycosidase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10537.11 Da        Isoelectric Point: 10.2849

>T287831 WP_005387908.1 NZ_LR134375:412438-412704 [Veillonella dispar]
MAYKLEFSKRFDKQFSKLDKSTQRYLFNWLIKNVDNVENPRYSGKSLTGNKTGLWRYRIGNYRVIADINDDRCIILALEV
GHRKDIYK

Download         Length: 267 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8499.71 Da        Isoelectric Point: 4.3700

>AT287831 WP_005387906.1 NZ_LR134375:412227-412448 [Veillonella dispar]
MANISVRLNEQEEELFKTYAEFMDETLSTLFKKALLEKIEDEFDLKVGQKALAEYKQDPVTYSVAEMRAKYGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S7YR27

Antitoxin

Source ID Structure
AlphaFold DB A0A2S7YQA8

References