Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 412227..412704 Replicon chromosome
Accession NZ_LR134375
Organism Veillonella dispar strain NCTC11831

Toxin (Protein)


Gene name relE Uniprot ID C4FSP2
Locus tag EL171_RS01820 Protein ID WP_005387908.1
Coordinates 412438..412704 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C4FSP1
Locus tag EL171_RS01815 Protein ID WP_005387906.1
Coordinates 412227..412448 (+) Length 74 a.a.

Genomic Context

EL171_RS01800EL171_RS01805EL171_RS01815EL171_RS01820EL171_RS01825EL171_RS01830EL171_RS01845EL171_RS01850EL171_RS01810EL171_RS01835
Location: 408232..409689 (1458 bp)
Type: Others
Protein ID: WP_005387899.1
Location: 409820..410338 (519 bp)
Type: Others
Protein ID: WP_005387901.1
Location: 412227..412448 (222 bp)
Type: Antitoxin
Protein ID: WP_005387906.1
Location: 412438..412704 (267 bp)
Type: Toxin
Protein ID: WP_005387908.1
Location: 412715..412927 (213 bp)
Type: Others
Protein ID: WP_005387910.1
Location: 412994..414079 (1086 bp)
Type: Others
Protein ID: WP_005387912.1
Location: 415262..416065 (804 bp)
Type: Others
Protein ID: WP_005387916.1
Location: 416077..417015 (939 bp)
Type: Others
Protein ID: WP_039969603.1
Location: 410379..411752 (1374 bp)
Type: Others
Protein ID: WP_005387903.1
Location: 414153..414944 (792 bp)
Type: Others
Protein ID: WP_005387914.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL171_RS01800408232..409689+1458WP_005387899.1hypothetical protein-
EL171_RS01805409820..410338+519WP_005387901.1hypothetical protein-
EL171_RS01810410379..411752-1374WP_005387903.1MFS transporter-
EL171_RS01815412227..412448+222WP_005387906.1hypothetical proteinAntitoxin
EL171_RS01820412438..412704+267WP_005387908.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EL171_RS01825412715..412927+213WP_005387910.1hypothetical protein-
EL171_RS01830412994..414079+1086WP_005387912.1hypothetical protein-
EL171_RS01835414153..414944-792WP_005387914.1carbon-nitrogen family hydrolase-
EL171_RS01845415262..416065+804WP_005387916.1polysaccharide deacetylase family protein-
EL171_RS01850416077..417015+939WP_039969603.1phosphodiester glycosidase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10537.11 Da        Isoelectric Point: 10.2849

>T287831 WP_005387908.1 NZ_LR134375:412438-412704 [Veillonella dispar]
MAYKLEFSKRFDKQFSKLDKSTQRYLFNWLIKNVDNVENPRYSGKSLTGNKTGLWRYRIGNYRVIADINDDRCIILALEV
GHRKDIYK

Download         Length: 267 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8499.71 Da        Isoelectric Point: 4.3700

>AT287831 WP_005387906.1 NZ_LR134375:412227-412448 [Veillonella dispar]
MANISVRLNEQEEELFKTYAEFMDETLSTLFKKALLEKIEDEFDLKVGQKALAEYKQDPVTYSVAEMRAKYGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A2S7YR27

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2S7YQA8

References