Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-DinJ
Location 105984..106544 Replicon chromosome
Accession NZ_LR134375
Organism Veillonella dispar strain NCTC11831

Toxin (Protein)


Gene name yafQ Uniprot ID C4FRV2
Locus tag EL171_RS00375 Protein ID WP_005387420.1
Coordinates 105984..106256 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C4FRV3
Locus tag EL171_RS00380 Protein ID WP_005387422.1
Coordinates 106263..106544 (-) Length 94 a.a.

Genomic Context

EL171_RS00345EL171_RS00350EL171_RS00355EL171_RS00360EL171_RS00365EL171_RS00385EL171_RS00390EL171_RS00395EL171_RS00400EL171_RS00375EL171_RS00380
Location: 101250..101990 (741 bp)
Type: Others
Protein ID: WP_005387396.1
Location: 102094..102588 (495 bp)
Type: Others
Protein ID: WP_005387397.1
Location: 102735..103727 (993 bp)
Type: Others
Protein ID: WP_005387399.1
Location: 103752..104225 (474 bp)
Type: Others
Protein ID: WP_005387404.1
Location: 104404..105342 (939 bp)
Type: Others
Protein ID: WP_005387412.1
Location: 106729..107361 (633 bp)
Type: Others
Protein ID: WP_005387423.1
Location: 107749..108156 (408 bp)
Type: Others
Protein ID: WP_009351901.1
Location: 108511..109631 (1121 bp)
Type: Others
Protein ID: Protein_73
Location: 109798..111006 (1209 bp)
Type: Others
Protein ID: WP_005387431.1
Location: 105984..106256 (273 bp)
Type: Toxin
Protein ID: WP_005387420.1
Location: 106263..106544 (282 bp)
Type: Antitoxin
Protein ID: WP_005387422.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL171_RS00345101250..101990+741WP_005387396.1ABC transporter ATP-binding protein-
EL171_RS00350102094..102588+495WP_005387397.1GyrI-like domain-containing protein-
EL171_RS00355102735..103727+993WP_005387399.1virulence RhuM family protein-
EL171_RS00360103752..104225+474WP_005387404.1HXXEE domain-containing protein-
EL171_RS00365104404..105342+939WP_005387412.1IS30 family transposase-
EL171_RS00375105984..106256-273WP_005387420.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
EL171_RS00380106263..106544-282WP_005387422.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
EL171_RS00385106729..107361+633WP_005387423.1hypothetical protein-
EL171_RS00390107749..108156+408WP_009351901.1hypothetical protein-
EL171_RS00395108511..109631+1121Protein_73IS1249 family transposase-
EL171_RS00400109798..111006+1209WP_005387431.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--109071..109631560


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-90)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10492.23 Da        Isoelectric Point: 9.7293

>T287830 WP_005387420.1 NZ_LR134375:c106256-105984 [Veillonella dispar]
MLRLVLSNKFKKDLKCSKKRGKDLNKLYSIITKLQNQTLLDPSYKDHPLTGNYEGFRELHVEPDWLLIYAIKDDILVLSL
TRTGSHSDLF

Download         Length: 273 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10173.73 Da        Isoelectric Point: 5.0931

>AT287830 WP_005387422.1 NZ_LR134375:c106544-106263 [Veillonella dispar]
MAKTASISLRIEPAVKAQLEALYASFGISVTDAINIFLHTSLMEGGFPFQPKQPRYNAETEAAIQETKDILAGKIKAKSY
ANVKEMIEDLGLE

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBC4FRV2

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A2S7ZR52

References