287801

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Rv0298-Rv0299/-
Location 57816..58339 Replicon chromosome
Accession NZ_LR134355
Organism Mycolicibacterium chitae strain NCTC10485

Toxin (Protein)


Gene name Rv0299 Uniprot ID -
Locus tag EL338_RS00285 Protein ID WP_126331927.1
Coordinates 58040..58339 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name Rv0298 Uniprot ID -
Locus tag EL338_RS00280 Protein ID WP_126331926.1
Coordinates 57816..58043 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL338_RS00250 52847..53173 + 327 WP_126331921.1 metalloregulator ArsR/SmtB family transcription factor -
EL338_RS00255 53183..53680 + 498 WP_126331922.1 SRPBCC domain-containing protein -
EL338_RS00260 53704..55056 - 1353 WP_126331923.1 TIGR01777 family oxidoreductase -
EL338_RS00265 55259..55747 - 489 WP_126331924.1 hypothetical protein -
EL338_RS00270 55924..56577 + 654 WP_126331925.1 response regulator transcription factor -
EL338_RS00275 56600..57805 + 1206 WP_126336582.1 sensor histidine kinase -
EL338_RS00280 57816..58043 + 228 WP_126331926.1 ribbon-helix-helix protein, CopG family Antitoxin
EL338_RS00285 58040..58339 + 300 WP_126331927.1 toxin Toxin
EL338_RS00290 58416..59171 - 756 WP_126331928.1 helix-turn-helix transcriptional regulator -
EL338_RS00295 59314..59730 + 417 WP_126331929.1 WhiB family transcriptional regulator -
EL338_RS00300 59740..60558 + 819 WP_126331930.1 C40 family peptidase -
EL338_RS00305 60609..60974 + 366 WP_126331931.1 DUF4226 domain-containing protein -
EL338_RS00310 61120..62544 + 1425 WP_126336583.1 DUF4226 domain-containing protein -
EL338_RS00315 62555..62863 + 309 WP_126331932.1 ESX-1 secretion-associated protein -
EL338_RS00320 62860..63165 + 306 WP_126331933.1 DUF2694 family protein -
EL338_RS26060 63184..63327 - 144 WP_170217407.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Ribbon-helix-helix protein, CopG

(6-39)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 10550.31 Da        Isoelectric Point: 4.6779

>T287801 WP_126331927.1 NZ_LR134355:58040-58339 [Mycolicibacterium chitae]
VMRPGDVAPRLDTEHELYVAVLSNSMHLTANTGRVITCPFIPGEIPADTMAMVVATERPRGVVVPELVQWLPVVALDAPI
GNIGADAVHETKTVLTALL

Download         Length: 300 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 7942.00 Da        Isoelectric Point: 4.5637

>AT287801 WP_126331926.1 NZ_LR134355:57816-58043 [Mycolicibacterium chitae]
MAKDKISVTVDAAVLAAADAHAAAAGLNRSEMIEQALRNESVRLALESYTTQTVPMLDIDSYAGMIYQANRSAGL

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References