287719

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 4495735..4496405 Replicon chromosome
Accession NZ_LR134334
Organism Pseudomonas chlororaphis strain NCTC7357

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL332_RS20020 Protein ID WP_124323278.1
Coordinates 4495735..4496163 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A3G7DZE9
Locus tag EL332_RS20025 Protein ID WP_009046453.1
Coordinates 4496160..4496405 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL332_RS19990 4490934..4491422 - 489 WP_124323274.1 DoxX family membrane protein -
EL332_RS19995 4491479..4492219 - 741 WP_124323275.1 SDR family oxidoreductase -
EL332_RS20000 4492349..4493239 + 891 WP_124323276.1 LysR family transcriptional regulator -
EL332_RS20005 4493364..4493546 + 183 WP_009041685.1 type II toxin-antitoxin system HicA family toxin -
EL332_RS20010 4493576..4493977 + 402 WP_025808441.1 type II toxin-antitoxin system HicB family antitoxin -
EL332_RS20015 4494568..4495605 + 1038 WP_124323277.1 L-glyceraldehyde 3-phosphate reductase -
EL332_RS20020 4495735..4496163 - 429 WP_124323278.1 type II toxin-antitoxin system VapC family toxin Toxin
EL332_RS20025 4496160..4496405 - 246 WP_009046453.1 plasmid stabilization protein Antitoxin
EL332_RS20030 4496545..4497384 - 840 WP_124323279.1 taurine dioxygenase -
EL332_RS20035 4497622..4498461 - 840 WP_124323280.1 taurine ABC transporter permease TauC -
EL332_RS20040 4498458..4499252 - 795 WP_023970012.1 taurine ABC transporter ATP-binding subunit -
EL332_RS20045 4499363..4500340 - 978 WP_124323281.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15862.37 Da        Isoelectric Point: 5.4577

>T287719 WP_124323278.1 NZ_LR134334:c4496163-4495735 [Pseudomonas chlororaphis]
MIVLDTNVLSELMHPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASALAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEI

Download         Length: 429 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9103.27 Da        Isoelectric Point: 6.2314

>AT287719 WP_009046453.1 NZ_LR134334:c4496405-4496160 [Pseudomonas chlororaphis]
MASLTIRNLDDHIKERLRIEAAHNGHSMEEEARLILRRALSRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3G7DZE9

References