287715

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4916255..4917074 Replicon chromosome
Accession NZ_LR134333
Organism Klebsiella oxytoca strain NCTC13727

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag EL226_RS23415 Protein ID WP_004110819.1
Coordinates 4916817..4917074 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag EL226_RS23410 Protein ID WP_047720343.1
Coordinates 4916255..4916806 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL226_RS23395 4912105..4913382 + 1278 WP_047720334.1 hypothetical protein -
EL226_RS23400 4913400..4914563 + 1164 WP_047720336.1 MFS transporter -
EL226_RS23405 4914609..4916237 - 1629 WP_047720339.1 SAM-dependent methyltransferase -
EL226_RS23410 4916255..4916806 - 552 WP_047720343.1 N-acetyltransferase Antitoxin
EL226_RS23415 4916817..4917074 - 258 WP_004110819.1 YjhX family toxin Toxin
EL226_RS23420 4917656..4918840 + 1185 WP_004099225.1 mannonate dehydratase -
EL226_RS23425 4918915..4920390 + 1476 WP_047720344.1 fructuronate reductase -
EL226_RS23430 4920526..4921302 + 777 WP_004099223.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(17-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T287715 WP_004110819.1 NZ_LR134333:c4917074-4916817 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20213.16 Da        Isoelectric Point: 7.0634

>AT287715 WP_047720343.1 NZ_LR134333:c4916806-4916255 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVAALLNDESAHPSLSLLAKHNGKAVGHILFTLATFKGESDSPMMH
ILAPLAVVPEYQGVGVGGLLIQRGIEHLKAMGSLAVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References