287674

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/ParE-RHH
Location 2778642..2779207 Replicon chromosome
Accession NZ_LR134321
Organism Shewanella baltica strain NCTC10737

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag EL185_RS11970 Protein ID WP_107947282.1
Coordinates 2778914..2779207 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID A0A448EM94
Locus tag EL185_RS11965 Protein ID WP_011716807.1
Coordinates 2778642..2778926 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL185_RS11925 2773901..2774092 - 192 WP_126493497.1 AlpA family transcriptional regulator -
EL185_RS11930 2774242..2774733 + 492 WP_197721157.1 DNA repair protein RadC -
EL185_RS11935 2774774..2775136 + 363 WP_126492066.1 hypothetical protein -
EL185_RS11940 2775267..2775623 + 357 WP_126492067.1 type IV toxin-antitoxin system YeeU family antitoxin -
EL185_RS11945 2775868..2776281 + 414 WP_126492068.1 DUF2787 domain-containing protein -
EL185_RS11950 2776472..2776879 + 408 WP_126492069.1 DUF2787 domain-containing protein -
EL185_RS11955 2776988..2777554 + 567 WP_126492070.1 site-specific integrase -
EL185_RS11960 2777633..2778355 + 723 WP_126492071.1 lecithin retinol acyltransferase family protein -
EL185_RS11965 2778642..2778926 + 285 WP_011716807.1 CopG family ribbon-helix-helix protein Antitoxin
EL185_RS11970 2778914..2779207 + 294 WP_107947282.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL185_RS11975 2779379..2780041 - 663 WP_126492072.1 inovirus Gp2 family protein -
EL185_RS11980 2780377..2781840 - 1464 WP_126492073.1 DUF3987 domain-containing protein -
EL185_RS11985 2781878..2782090 - 213 WP_126492074.1 AlpA family phage regulatory protein -
EL185_RS11990 2782209..2783285 - 1077 WP_126492075.1 cytoplasmic protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11152.68 Da        Isoelectric Point: 5.8404

>T287674 WP_107947282.1 NZ_LR134321:2778914-2779207 [Shewanella baltica]
MPQIIFTATALRDLERLREFLRSKNPPAAQRAASAIINTIRKLESYPDIGRPIDDNDFNFRELLIDFGDTGYLAMYQYDG
GERLTVLCVRHQKEAGY

Download         Length: 294 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10955.25 Da        Isoelectric Point: 5.9920

>AT287674 WP_011716807.1 NZ_LR134321:2778642-2778926 [Shewanella baltica]
MSTIKPVSVKLDADIKARVEHLAETRKRSSHWMMREAIREYVEREEKREALQQEALRAWEEHQTSGLHVTGDEVVSWLES
WGSENEQAAPTCHK

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A448EM94

References