287668

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 702765..704306 Replicon chromosome
Accession NZ_LR134321
Organism Shewanella baltica strain NCTC10737

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag EL185_RS03140 Protein ID WP_126491147.1
Coordinates 703005..704306 (+) Length 434 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag EL185_RS03135 Protein ID WP_126493436.1
Coordinates 702765..703001 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL185_RS03115 697955..698848 - 894 WP_126491143.1 hypothetical protein -
EL185_RS03120 698849..699418 - 570 WP_126491144.1 recombinase family protein -
EL185_RS03125 699682..700665 + 984 WP_126491145.1 hypothetical protein -
EL185_RS03130 700683..701975 - 1293 WP_126491146.1 tyrosine-type recombinase/integrase -
EL185_RS03135 702765..703001 + 237 WP_126493436.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
EL185_RS03140 703005..704306 + 1302 WP_126491147.1 HipA domain-containing protein Toxin
EL185_RS03145 704480..704691 + 212 Protein_598 cytochrome C -
EL185_RS03150 704786..705265 + 480 WP_126491148.1 hypothetical protein -
EL185_RS03160 705812..706198 + 387 WP_006086103.1 carboxymuconolactone decarboxylase family protein -
EL185_RS03165 706341..706592 - 252 WP_006083102.1 DUF2999 domain-containing protein -
EL185_RS03170 706957..708453 + 1497 WP_126491149.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(9-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(11-64)


Sequences

Toxin        


Download         Length: 434 a.a.        Molecular weight: 48722.03 Da        Isoelectric Point: 5.1856

>T287668 WP_126491147.1 NZ_LR134321:703005-704306 [Shewanella baltica]
MSTSKKLTLEMHLGDLIIGELSFDAMTDTFAVHYTKDWQQSGFPLSPTIPLDGTGSSSQISMFLVNLLPENKGLDYLIES
LGVSKGNTFALIRAIGLDTAGAVAFVPKGTLLPETQLRPIKAEEVIQRIEDPTMWPMEIWDGKPRLSLAGVQPKLNLFYN
GEEFAFAEGALSSTHIVKFEKYRHLVLNEFMTMRLAKAIGMNVANVDIVHFGDYKVLCVERFDRRYMPNEQRVLRRHIVD
SCQALGFSVSKKYERNFGSGRDVKDIREGVSFNRLFSLAVKCRNPVAAKQDMLQWALFNLLTGNADAHGKNYSFFMTPSG
MEPTPWYDLVSVAMYEDFEQQLAMAIDDEFDPNSIYAYQLAAFIDGLDLPKNLLISNLTTMARRISQAIDGVISMLPALD
ESETVFVAHYKVQLLARCDRYLSFAAEIRDVEV

Download         Length: 1302 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8515.84 Da        Isoelectric Point: 6.2339

>AT287668 WP_126493436.1 NZ_LR134321:702765-703001 [Shewanella baltica]
MASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIEIVSAQTSDTETNGWY

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References