Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 2444332..2444851 Replicon chromosome
Accession NZ_LR134313
Organism Neisseria canis strain NCTC10296

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL143_RS11560 Protein ID WP_085389274.1
Coordinates 2444585..2444851 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag EL143_RS11555 Protein ID WP_085416241.1
Coordinates 2444332..2444598 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL143_RS11525 2439574..2440560 - 987 Protein_2275 biotin synthase BioB -
EL143_RS11530 2440926..2441873 - 948 WP_126326789.1 hypothetical protein -
EL143_RS11535 2441918..2442445 - 528 WP_085416239.1 alpha/beta hydrolase -
EL143_RS11540 2442461..2442658 - 198 WP_004283984.1 DUF1737 domain-containing protein -
EL143_RS11545 2442795..2443238 + 444 WP_085416240.1 hypothetical protein -
EL143_RS11550 2443387..2444163 - 777 WP_085416279.1 exodeoxyribonuclease III -
EL143_RS11555 2444332..2444598 + 267 WP_085416241.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL143_RS11560 2444585..2444851 + 267 WP_085389274.1 type II toxin-antitoxin system YafQ family toxin Toxin
EL143_RS11565 2444962..2447475 - 2514 WP_085416242.1 TonB-dependent receptor -
EL143_RS11570 2447706..2448359 + 654 WP_085416243.1 hypothetical protein -
EL143_RS11575 2448400..2449087 - 688 Protein_2285 chromate transporter -
EL143_RS11580 2449067..2449708 + 642 WP_085416244.1 orotate phosphoribosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10155.68 Da        Isoelectric Point: 7.3242

>T287632 WP_085389274.1 NZ_LR134313:2444585-2444851 [Neisseria canis]
MKAIEFSNAFKRDFKKYPALALSTRWIEALYCICSEQTLPPKFCDHALTGNWHGFRDCHIEPDLVLIYRHTENTVELARI
GTHSALFG

Download         Length: 267 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9582.77 Da        Isoelectric Point: 4.5183

>AT287632 WP_085416241.1 NZ_LR134313:2444332-2444598 [Neisseria canis]
MAANALVSVRINEDVKNQASAVLAGAGLTISDVIRMTLTKIATEQRFSFDYQPNAETARVLTAMQNGTETLHRADSVEAL
MERLNESD

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References