Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
Location | 2691359..2692401 | Replicon | chromosome |
Accession | NZ_LR134309 | ||
Organism | Pseudomonas aeruginosa strain NCTC12903 |
Toxin (Protein)
Gene name | PP_4152 | Uniprot ID | - |
Locus tag | EL344_RS13315 | Protein ID | WP_003153636.1 |
Coordinates | 2691826..2692401 (+) | Length | 192 a.a. |
Antitoxin (Protein)
Gene name | PP_4151 | Uniprot ID | I3TV68 |
Locus tag | EL344_RS13310 | Protein ID | WP_003050245.1 |
Coordinates | 2691359..2691829 (+) | Length | 157 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EL344_RS13275 | 2686751..2688169 | - | 1419 | WP_006226029.1 | TIGR03752 family integrating conjugative element protein | - |
EL344_RS13280 | 2688159..2689070 | - | 912 | WP_006226028.1 | TIGR03749 family integrating conjugative element protein | - |
EL344_RS13285 | 2689067..2689759 | - | 693 | WP_003090182.1 | TIGR03746 family integrating conjugative element protein | - |
EL344_RS13290 | 2689756..2690154 | - | 399 | WP_003050133.1 | TIGR03750 family conjugal transfer protein | - |
EL344_RS13295 | 2690166..2690525 | - | 360 | WP_003090173.1 | TIGR03745 family integrating conjugative element membrane protein | - |
EL344_RS13300 | 2690542..2690775 | - | 234 | WP_003090170.1 | TIGR03758 family integrating conjugative element protein | - |
EL344_RS13305 | 2690772..2691155 | - | 384 | WP_003090167.1 | RAQPRD family integrative conjugative element protein | - |
EL344_RS13310 | 2691359..2691829 | + | 471 | WP_003050245.1 | helix-turn-helix domain-containing protein | Antitoxin |
EL344_RS13315 | 2691826..2692401 | + | 576 | WP_003153636.1 | PIN domain-containing protein | Toxin |
EL344_RS13320 | 2692419..2693333 | + | 915 | WP_016852809.1 | AAA family ATPase | - |
EL344_RS13325 | 2693330..2693800 | + | 471 | WP_003090160.1 | hypothetical protein | - |
EL344_RS13330 | 2693797..2694297 | + | 501 | WP_003090159.1 | hypothetical protein | - |
EL344_RS13335 | 2694297..2695199 | + | 903 | WP_003090158.1 | nucleotidyltransferase domain-containing protein | - |
EL344_RS13340 | 2695238..2695963 | + | 726 | WP_003050273.1 | CBASS effector endonuclease NucC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 2616795..2738499 | 121704 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 192 a.a. Molecular weight: 21629.78 Da Isoelectric Point: 5.9995
>T287585 WP_003153636.1 NZ_LR134309:2691826-2692401 [Pseudomonas aeruginosa]
MRHSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSQAIHEEWKRNLLINRPDLTRVQVDRTSDLMDRAIPDGLVEGY
EALVAGLTLPDPNDRHVLAAAIRCGASVIVTFNERDFPNDLLAPYGIESQHPDEFVDNLLDLDAAAVVSAAQRQRAQLKH
PPIDVDRYLEILLRQGLVQTTKVLATYRTIL
MRHSPFTAVYDACVLYPAPLRDFLMWLGLSGRFRARWSQAIHEEWKRNLLINRPDLTRVQVDRTSDLMDRAIPDGLVEGY
EALVAGLTLPDPNDRHVLAAAIRCGASVIVTFNERDFPNDLLAPYGIESQHPDEFVDNLLDLDAAAVVSAAQRQRAQLKH
PPIDVDRYLEILLRQGLVQTTKVLATYRTIL
Download Length: 576 bp
Antitoxin
Download Length: 157 a.a. Molecular weight: 17245.62 Da Isoelectric Point: 6.3803
>AT287585 WP_003050245.1 NZ_LR134309:2691359-2691829 [Pseudomonas aeruginosa]
MTTATAQSKMTLPAAGEVKAAVQGQRALAAYLATQFETQHIQIFDDHKQAHQVELPTSALRLLVDILAELADGNAVKVVP
VHAELTTQEAADLLNVSRPHFVKLLEDGVLAFHRTGKHRRVRFADLMQYKEARERASEQAMAELAQQSQELGMGYE
MTTATAQSKMTLPAAGEVKAAVQGQRALAAYLATQFETQHIQIFDDHKQAHQVELPTSALRLLVDILAELADGNAVKVVP
VHAELTTQEAADLLNVSRPHFVKLLEDGVLAFHRTGKHRRVRFADLMQYKEARERASEQAMAELAQQSQELGMGYE
Download Length: 471 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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