Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5758616..5759298 Replicon chromosome
Accession NZ_LR134302
Organism Achromobacter spanius strain NCTC13519

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL258_RS26260 Protein ID WP_100856032.1
Coordinates 5758616..5759050 (-) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL258_RS26265 Protein ID WP_100856031.1
Coordinates 5759047..5759298 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL258_RS26235 5754293..5755282 - 990 WP_100856036.1 DMT family transporter -
EL258_RS26240 5755417..5756241 - 825 WP_100857775.1 AraC family transcriptional regulator -
EL258_RS26245 5756385..5757659 - 1275 WP_100856035.1 RNA polymerase sigma factor -
EL258_RS26250 5757656..5758063 - 408 WP_100856034.1 VOC family protein -
EL258_RS26255 5758082..5758492 - 411 WP_100856033.1 YciI family protein -
EL258_RS26260 5758616..5759050 - 435 WP_100856032.1 type II toxin-antitoxin system VapC family toxin Toxin
EL258_RS26265 5759047..5759298 - 252 WP_100856031.1 Arc family DNA-binding protein Antitoxin
EL258_RS26270 5759398..5759751 - 354 WP_100856030.1 dehydrogenase -
EL258_RS26275 5759917..5760894 - 978 WP_100856029.1 OmpA family protein -
EL258_RS26280 5760891..5761796 - 906 WP_100856028.1 MotA/TolQ/ExbB proton channel family protein -
EL258_RS26285 5762095..5763909 + 1815 WP_100856027.1 NYN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin

Arc-like DNA binding domain

(10-46)


Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 15218.44 Da        Isoelectric Point: 5.5556

>T287527 WP_100856032.1 NZ_LR134302:c5759050-5758616 [Achromobacter spanius]
MILLDTNVISEPLRQAPADAVIEWIDRQPLETLFLSAVTVAELRFGVACMPVGKRRDALHGDLEQRVLALFAGRVLAFDT
AASLEYATLMARARASGQSIGGPDGYIAATAAAHGMSVATRDIAPFEAAGVSVINPWGASHPPH

Download         Length: 435 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9228.57 Da        Isoelectric Point: 8.8737

>AT287527 WP_100856031.1 NZ_LR134302:c5759298-5759047 [Achromobacter spanius]
MPMLTVRNISEEVHRALRVRAAQHGRSTEAEVRAILEDAVKPEGRVKLGSLLAQIGRQAKLTEEEAALFDQRDKAPAAPP
RFE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References