Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1930744..1931317 Replicon chromosome
Accession NZ_LR134302
Organism Achromobacter spanius strain NCTC13519

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL258_RS08740 Protein ID WP_100854122.1
Coordinates 1930744..1931031 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL258_RS08745 Protein ID WP_100854121.1
Coordinates 1931018..1931317 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL258_RS08730 1927511..1928281 - 771 WP_100854124.1 glucose 1-dehydrogenase -
EL258_RS08735 1928505..1930628 - 2124 WP_100854123.1 TonB-dependent receptor -
EL258_RS08740 1930744..1931031 - 288 WP_100854122.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL258_RS08745 1931018..1931317 - 300 WP_100854121.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL258_RS08750 1931541..1932020 + 480 WP_100854120.1 VOC family protein -
EL258_RS08755 1932086..1933135 - 1050 WP_100854119.1 ABC transporter substrate-binding protein -
EL258_RS08760 1933231..1934208 - 978 WP_100854118.1 GTP-binding protein -
EL258_RS08765 1934210..1935868 - 1659 WP_100854117.1 amidohydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-52)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10864.61 Da        Isoelectric Point: 9.5280

>T287523 WP_100854122.1 NZ_LR134302:c1931031-1930744 [Achromobacter spanius]
VPVLEWRETAREDLLAIVDYISDDSPAAALRLVDEIQKKVVKLRERPRLYRAGRVAGTREMVIRPNYLVVYAESPRAVTI
LRVLHAAQQWPLDSA

Download         Length: 288 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10636.34 Da        Isoelectric Point: 10.1426

>AT287523 WP_100854121.1 NZ_LR134302:c1931317-1931018 [Achromobacter spanius]
MAPTSMLHVRVDDKLKAEAAEKLANVGLTISDAVRILLTRVAKEGGLPAGLAVDALSYDSWFRAKVQEALADTRPPVAHE
AVMDEARALISKKKRRAGS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References