Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1368133..1368674 Replicon chromosome
Accession NZ_LR134302
Organism Achromobacter spanius strain NCTC13519

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL258_RS06185 Protein ID WP_100854560.1
Coordinates 1368133..1368408 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL258_RS06190 Protein ID WP_100854559.1
Coordinates 1368408..1368674 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL258_RS06165 1363593..1364606 + 1014 WP_100854564.1 helix-turn-helix domain-containing protein -
EL258_RS06170 1364626..1365936 - 1311 WP_100854563.1 MHS family MFS transporter -
EL258_RS06175 1366046..1366672 - 627 WP_100854562.1 glutathione S-transferase family protein -
EL258_RS06180 1366968..1368017 + 1050 WP_100854561.1 alpha/beta hydrolase -
EL258_RS06185 1368133..1368408 - 276 WP_100854560.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL258_RS06190 1368408..1368674 - 267 WP_100854559.1 ribbon-helix-helix domain-containing protein Antitoxin
EL258_RS06195 1368832..1369731 + 900 WP_100854558.1 helix-turn-helix domain-containing protein -
EL258_RS06200 1369860..1371545 + 1686 WP_100854557.1 thiamine pyrophosphate-binding protein -
EL258_RS06205 1371630..1372622 + 993 WP_100854556.1 tripartite tricarboxylate transporter substrate binding protein -
EL258_RS06210 1372659..1372976 + 318 WP_100854555.1 NIPSNAP family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10443.20 Da        Isoelectric Point: 9.6223

>T287522 WP_100854560.1 NZ_LR134302:c1368408-1368133 [Achromobacter spanius]
MELKWTSKALSDLAPLYEFLAPANAPAAARAVQALVKAPGILLTHPRIGEQLFQFEPREVRKILVGQFEVRYEIQGSIIY
VLRLWHSREER

Download         Length: 276 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9779.24 Da        Isoelectric Point: 5.6939

>AT287522 WP_100854559.1 NZ_LR134302:c1368674-1368408 [Achromobacter spanius]
MPVATKVLTAHVPLPLAEKVDQMAARLERSRGWIMKQALSAWIAQEEERDRLTQEALADVEAGRVVDHQAVQAWAESLGT
DKPLPVPR

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References