287516

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 3983212..3983820 Replicon chromosome
Accession NZ_LR134300
Organism Pseudomonas fluorescens strain NCTC10783

Toxin (Protein)


Gene name PfiT Uniprot ID A0A3S4N9Q9
Locus tag EL286_RS19155 Protein ID WP_031672658.1
Coordinates 3983212..3983559 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A0B0C355
Locus tag EL286_RS19160 Protein ID WP_003114155.1
Coordinates 3983569..3983820 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL286_RS19125 3978571..3978843 + 273 WP_003120794.1 cysteine-rich CWC family protein -
EL286_RS19130 3978843..3979535 + 693 WP_003098362.1 16S rRNA pseudouridine(516) synthase -
EL286_RS19135 3979671..3980714 + 1044 WP_003098363.1 L,D-transpeptidase -
EL286_RS19140 3980794..3981531 + 738 WP_003085453.1 murein L,D-transpeptidase catalytic domain family protein -
EL286_RS19145 3981983..3982885 + 903 WP_003098365.1 (R)-3-hydroxydecanoyl-ACP:CoA transacylase -
EL286_RS19155 3983212..3983559 - 348 WP_031672658.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL286_RS19160 3983569..3983820 - 252 WP_003114155.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EL286_RS19165 3984034..3985017 - 984 WP_057392395.1 tyrosine-type recombinase/integrase -
EL286_RS19170 3985017..3986309 - 1293 WP_003123045.1 hypothetical protein -
EL286_RS19175 3986568..3987830 - 1263 WP_057392396.1 hypothetical protein -
EL286_RS19180 3987832..3988182 - 351 WP_003159569.1 DUF2523 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3983212..3998391 15179


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-100)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12898.69 Da        Isoelectric Point: 4.5143

>T287516 WP_031672658.1 NZ_LR134300:c3983559-3983212 [Pseudomonas fluorescens]
MSPVVIRFTDTAEQSIEDQVHHLAPFQGAQAALQSVLSLLDEIEEKISLAPKGYPVSQQASLLGVLSYRELNTGPYRVFY
EFHEEQGEAAVILVLRQKQSVEQQLIRYCLVGPIE

Download         Length: 348 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9442.79 Da        Isoelectric Point: 9.4808

>AT287516 WP_003114155.1 NZ_LR134300:c3983820-3983569 [Pseudomonas fluorescens]
MRVETISYLKRHAADLDLSEPMVVTQNGVPAYVVESYAERKQRDEAIALVKLLAIGSRQYAEGKHRSVDDLKARLSRRFA
QPE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S4N9Q9

Antitoxin

Source ID Structure
AlphaFold DB A0A0B0C355

References