Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966013..1966284 Replicon chromosome
Accession NZ_LR134296
Organism Escherichia coli strain NCTC9041

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966143..1966246 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966013..1966284 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL151_RS09420 1962568..1963230 - 663 WP_000944256.1 exodeoxyribonuclease X -
EL151_RS09425 1963254..1963910 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EL151_RS09430 1964012..1964242 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EL151_RS09435 1964381..1964755 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EL151_RS09440 1964759..1965631 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
EL151_RS09445 1965644..1965985 + 342 WP_000976476.1 YebY family protein -
- 1966013..1966284 - 272 - - Antitoxin
- 1966143..1966246 + 104 - - Toxin
EL151_RS09450 1966381..1967037 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
EL151_RS09455 1967038..1967229 - 192 WP_000457842.1 YebW family protein -
EL151_RS09460 1967334..1967570 - 237 WP_001295499.1 DUF1480 family protein -
EL151_RS09465 1967688..1969127 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T287489 NZ_LR134296:1966143-1966246 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT287489 NZ_LR134296:c1966284-1966013 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References