Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelB(antitoxin)
Location 443258..443882 Replicon chromosome
Accession NZ_LR134293
Organism Streptococcus canis strain NCTC12191

Toxin (Protein)


Gene name parE Uniprot ID A0A8H2NG61
Locus tag EL097_RS02155 Protein ID WP_003046168.1
Coordinates 443258..443605 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A8H2NIT0
Locus tag EL097_RS02160 Protein ID WP_003046166.1
Coordinates 443595..443882 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL097_RS02145 439320..441620 - 2301 WP_003046173.1 penicillin-binding protein PBP1B -
EL097_RS02150 441727..442986 + 1260 WP_003046171.1 tyrosine--tRNA ligase -
EL097_RS02155 443258..443605 - 348 WP_003046168.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL097_RS02160 443595..443882 - 288 WP_003046166.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL097_RS02165 443951..444328 - 378 WP_003046164.1 DUF1492 domain-containing protein -
EL097_RS02170 444318..444665 - 348 WP_003046162.1 DUF1492 domain-containing protein -
EL097_RS02180 445062..445550 - 489 WP_129544917.1 hypothetical protein -
EL097_RS02185 445624..446181 - 558 WP_003045777.1 hypothetical protein -
EL097_RS10545 446183..446356 - 174 WP_003045775.1 hypothetical protein -
EL097_RS02190 446362..446535 - 174 WP_003046156.1 hypothetical protein -
EL097_RS02195 446870..448372 - 1503 WP_003046154.1 DNA primase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(12-108)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-63)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 13231.99 Da        Isoelectric Point: 5.5796

>T287459 WP_003046168.1 NZ_LR134293:c443605-443258 [Streptococcus canis]
MVSDNKTHSLIIPETVQEQLRAIKSYIETTYFSEQAGANTVNNILYGLERLEFFPEAGFNADDRVGETIYPPHNTRCIVL
GDYLAFYHILEDGKAVFVSDIIHSKQDYIRLFKKK

Download         Length: 348 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10634.04 Da        Isoelectric Point: 4.8430

>AT287459 WP_003046166.1 NZ_LR134293:c443882-443595 [Streptococcus canis]
MHVLEKNTQVNFKTNSDLLEKAKAIIAAQNLDMTASFNLFLENIVQNKALPFETDTDKERAELLAGLRAEIAKSFDDLEH
GRVYNASEVRANLGI

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References