Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 653493..653638 Replicon chromosome
Accession NZ_LR134280
Organism Klebsiella pneumoniae strain NCTC9793

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 653529..653631 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 653493..653638 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL169_RS03550 648624..650683 + 2060 Protein_587 oligopeptidase B -
EL169_RS03555 650687..651346 - 660 WP_021440386.1 exodeoxyribonuclease X -
EL169_RS03560 651425..651655 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EL169_RS03565 651768..652142 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EL169_RS03570 652146..653015 + 870 WP_064172307.1 copper homeostasis membrane protein CopD -
EL169_RS03575 653032..653370 + 339 WP_002911404.1 YebY family protein -
- 653493..653638 - 146 - - Antitoxin
- 653529..653631 + 103 - - Toxin
EL169_RS26865 654005..654148 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EL169_RS03585 654253..655221 - 969 WP_004151446.1 VirK/YbjX family protein -
EL169_RS03590 655378..656031 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
EL169_RS03595 656028..656219 - 192 WP_002911395.1 YebW family protein -
EL169_RS03600 656317..656556 - 240 WP_002911393.1 YebV family protein -
EL169_RS03605 656672..658105 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T287441 NZ_LR134280:653529-653631 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT287441 NZ_LR134280:c653638-653493 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References