Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2172455..2172700 Replicon chromosome
Accession NZ_LR134270
Organism Escherichia marmotae strain NCTC8196

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2172583..2172686 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2172455..2172700 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL146_RS10575 2169008..2169670 - 663 WP_000944296.1 exodeoxyribonuclease X -
EL146_RS10580 2169695..2170351 - 657 WP_000122137.1 carbon-nitrogen hydrolase family protein -
EL146_RS10585 2170452..2170682 - 231 WP_000916764.1 DNA polymerase III subunit theta -
EL146_RS10590 2170821..2171195 + 375 WP_016248632.1 CopC domain-containing protein YobA -
EL146_RS10595 2171199..2172071 + 873 WP_000879335.1 copper homeostasis membrane protein CopD -
EL146_RS10600 2172084..2172425 + 342 WP_000976465.1 YebY family protein -
- 2172455..2172700 - 246 - - Antitoxin
- 2172583..2172686 + 104 - - Toxin
EL146_RS10605 2172835..2173491 + 657 WP_000806226.1 protein-serine/threonine phosphatase -
EL146_RS10610 2173492..2173683 - 192 WP_001516263.1 YebW family protein -
EL146_RS10615 2173788..2174024 - 237 WP_001516264.1 DUF1480 family protein -
EL146_RS10620 2174140..2175579 - 1440 WP_024193571.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2080108..2175621 95513
- inside Prophage - - 2079637..2173491 93854


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T287417 NZ_LR134270:2172583-2172686 [Escherichia marmotae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 246 bp

>AT287417 NZ_LR134270:c2172700-2172455 [Escherichia marmotae]
CTGGCTTTATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCG
CTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTCCGCGCG
TAAAGTGGTCAGAAAAAAAGCGCGTTTATCATCCTCTAAAATGTTAAAAACCGCCCATTCTGGTGAAAGCACCCGGGCGG
TTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References