Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sezT-pezT/zeta-couple_hipB
Location 1099394..1100646 Replicon chromosome
Accession NZ_LR134265
Organism Streptococcus agalactiae strain NCTC8184

Toxin (Protein)


Gene name sezT Uniprot ID -
Locus tag EL071_RS05785 Protein ID WP_115252829.1
Coordinates 1099870..1100646 (+) Length 259 a.a.

Antitoxin (Protein)


Gene name pezT Uniprot ID -
Locus tag EL071_RS05780 Protein ID WP_000578851.1
Coordinates 1099394..1099870 (+) Length 159 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL071_RS05740 1094953..1095762 + 810 WP_000200962.1 hypothetical protein -
EL071_RS05745 1095832..1096131 + 300 WP_000195241.1 hypothetical protein -
EL071_RS05750 1096146..1096436 + 291 WP_000893078.1 hypothetical protein -
EL071_RS05755 1096547..1097185 + 639 WP_000932871.1 hypothetical protein -
EL071_RS05760 1097224..1098312 + 1089 WP_000196746.1 toprim domain-containing protein -
EL071_RS05765 1098366..1098593 + 228 WP_000110925.1 hypothetical protein -
EL071_RS05770 1098597..1098992 + 396 WP_000159225.1 hypothetical protein -
EL071_RS05775 1099036..1099323 + 288 WP_000765214.1 hypothetical protein -
EL071_RS05780 1099394..1099870 + 477 WP_000578851.1 helix-turn-helix domain-containing protein Antitoxin
EL071_RS05785 1099870..1100646 + 777 WP_115252829.1 zeta toxin family protein Toxin
EL071_RS05790 1100630..1101439 + 810 WP_032459422.1 DUF1837 domain-containing protein -
EL071_RS05795 1101436..1104518 + 3083 Protein_1056 DEAD/DEAH box helicase -
EL071_RS05805 1104947..1105306 + 360 WP_000529540.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(27-215)

Antitoxin

Cro/C1-type helix-turn-helix domain

(3-60)


Sequences

Toxin        


Download         Length: 259 a.a.        Molecular weight: 29508.28 Da        Isoelectric Point: 6.5044

>T287401 WP_115252829.1 NZ_LR134265:1099870-1100646 [Streptococcus agalactiae]
MALADYHQDDFDFALKRTIRSLTRGKETSVNPNAILLGGQSGAGKTTIHRIKQKEFQGNIVIIDGDSYRSLHPNYLALQE
EYSKDSVDYTKGFAGKMVEHLVDELSKQGYHLLIEGTLRTAEVRRKTAQLLKSRGYQVSLALIATKPELSYLSTLIRYEE
VYAVNPNQARATPKEHHDAIVEHLVDNLRELETDKLFDQIQIYQRDRRCVYDSETDKGSAADVLQECLFGKWSKVEEEMM
KVGQEQLREVGRRNEKDA

Download         Length: 777 bp

Antitoxin


Download         Length: 159 a.a.        Molecular weight: 18088.56 Da        Isoelectric Point: 4.4289

>AT287401 WP_000578851.1 NZ_LR134265:1099394-1099870 [Streptococcus agalactiae]
MIGENIKSLRKTHDLTQPEFAKIVGISRNSLSRYENGTSSVTTELIDCICQKFNVSYVDIVGEEKMLTPVEDYQLTLKIE
VIKERGAAILSQLYRYQDSQGIAFDDETNPWILMSDDLSDLINTKIYLVNTFDEVERYNGYLDGIERMLVLARHQVVA

Download         Length: 477 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References