Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1041739..1042520 Replicon chromosome
Accession NZ_LR134263
Organism Staphylococcus delphini strain NCTC12225

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag EL101_RS13215 Protein ID WP_164715568.1
Coordinates 1042359..1042520 (+) Length 54 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag EL101_RS04815 Protein ID WP_096598606.1
Coordinates 1041739..1042338 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL101_RS04795 1037610..1039070 + 1461 WP_096598598.1 ABC transporter substrate-binding protein/permease -
EL101_RS04800 1039063..1039788 + 726 WP_096598600.1 amino acid ABC transporter ATP-binding protein -
EL101_RS04805 1039946..1041076 + 1131 WP_096598602.1 tRNA epoxyqueuosine(34) reductase QueG -
EL101_RS04810 1041076..1041546 + 471 WP_096598604.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
EL101_RS04815 1041739..1042338 + 600 WP_096598606.1 glucosamine-6-phosphate isomerase Antitoxin
EL101_RS13215 1042359..1042520 + 162 WP_164715568.1 hypothetical protein Toxin
EL101_RS04820 1042642..1043085 + 444 WP_096598608.1 hypothetical protein -
EL101_RS04825 1043313..1044698 + 1386 WP_096598610.1 class II fumarate hydratase -
EL101_RS04830 1044719..1046245 + 1527 WP_096598612.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(132-197)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 6305.79 Da        Isoelectric Point: 4.1725

>T287396 WP_164715568.1 NZ_LR134263:1042359-1042520 [Staphylococcus delphini]
MKDEQKHYDNEMVDSFDDVVELGKEMEQISEANDEEKLNQSHDSKVRFDKDTK

Download         Length: 162 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22214.23 Da        Isoelectric Point: 5.8283

>AT287396 WP_096598606.1 NZ_LR134263:1041739-1042338 [Staphylococcus delphini]
MAMNFKVFKDAETAATFTADILRKQLNNNPTSIVGFHLNQEEAPVLDALKKDVDRHSVDFSQIHVLDYDAQQSYYQALGV
PEKQIHHVPEDEKVEAFIKHHAKTKDNKGKLTLQVVTIDTEGQIGIPMNDALLPAREIIVVVTGAAKAEQVKKLYEENGN
TTFIPSALKSHRMVTVVLDEVAAQGLPEDVRNYFTSLYA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References