Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1917752..1918023 Replicon chromosome
Accession NZ_LR134248
Organism Escherichia coli strain NCTC10537

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1917882..1917985 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1917752..1918023 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL141_RS09150 1914308..1914970 - 663 WP_000944245.1 exodeoxyribonuclease X -
EL141_RS09155 1914994..1915650 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
EL141_RS09160 1915752..1915982 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EL141_RS09165 1916121..1916495 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EL141_RS09170 1916499..1917371 + 873 WP_000879293.1 copper homeostasis membrane protein CopD -
EL141_RS09175 1917384..1917725 + 342 WP_000976472.1 YebY family protein -
- 1917752..1918023 - 272 - - Antitoxin
- 1917882..1917985 + 104 - - Toxin
EL141_RS09180 1918120..1918776 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
EL141_RS09185 1918777..1918968 - 192 WP_001296140.1 YebW family protein -
EL141_RS09190 1919073..1919309 - 237 WP_001295499.1 DUF1480 family protein -
EL141_RS09195 1919427..1920866 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T287382 NZ_LR134248:1917882-1917985 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT287382 NZ_LR134248:c1918023-1917752 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References