Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2899918..2900189 Replicon chromosome
Accession NZ_LR134247
Organism Escherichia coli strain NCTC9040

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2899956..2900059 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2899918..2900189 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL149_RS14650 2897075..2898514 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EL149_RS14655 2898632..2898868 + 237 WP_001295499.1 DUF1480 family protein -
EL149_RS14660 2898973..2899164 + 192 WP_000457842.1 YebW family protein -
EL149_RS14665 2899165..2899821 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2899918..2900189 + 272 - - Antitoxin
- 2899956..2900059 - 104 - - Toxin
EL149_RS14670 2900217..2900558 - 342 WP_000976476.1 YebY family protein -
EL149_RS14675 2900571..2901443 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
EL149_RS14680 2901447..2901821 - 375 WP_000168747.1 CopC domain-containing protein YobA -
EL149_RS14685 2901960..2902190 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EL149_RS14690 2902292..2902948 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EL149_RS14695 2902972..2903634 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T287368 NZ_LR134247:c2900059-2899956 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT287368 NZ_LR134247:2899918-2900189 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References