Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) TsdAT/-
Location 809041..809551 Replicon chromosome
Accession NZ_LR134244
Organism Staphylococcus warneri strain NCTC7291

Toxin (Protein)


Gene name TsdT Uniprot ID A0A364UNH7
Locus tag EL075_RS03895 Protein ID WP_002466743.1
Coordinates 809345..809551 (+) Length 69 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID A0A364UNN3
Locus tag EL075_RS03890 Protein ID WP_002466760.1
Coordinates 809041..809334 (+) Length 98 a.a.

Genomic Context


EL075_RS03865EL075_RS03870EL075_RS03875EL075_RS03890EL075_RS03895EL075_RS03900EL075_RS03910EL075_RS03915EL075_RS03880EL075_RS03885EL075_RS03905
Location: 804167..804958 (792 bp)
Type: Others
Protein ID: WP_126403124.1
Location: 804959..805600 (642 bp)
Type: Others
Protein ID: WP_015364827.1
Location: 805689..806558 (870 bp)
Type: Others
Protein ID: WP_002466746.1
Location: 809041..809334 (294 bp)
Type: Antitoxin
Protein ID: WP_002466760.1
Location: 809345..809551 (207 bp)
Type: Toxin
Protein ID: WP_002466743.1
Location: 809690..809827 (138 bp)
Type: Others
Protein ID: WP_002466770.1
Location: 811515..812585 (1071 bp)
Type: Others
Protein ID: WP_002466764.1
Location: 812601..813962 (1362 bp)
Type: Others
Protein ID: WP_002466757.1
Location: 806596..807240 (645 bp)
Type: Others
Protein ID: WP_002466781.1
Location: 807368..808852 (1485 bp)
Type: Others
Protein ID: WP_002466786.1
Location: 809967..811157 (1191 bp)
Type: Others
Protein ID: WP_002466775.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EL075_RS03865804167..804958+792WP_126403124.1hydroxyethylthiazole kinase-
EL075_RS03870804959..805600+642WP_015364827.1thiamine phosphate synthase-
EL075_RS03875805689..806558+870WP_002466746.1membrane protein insertase YidC-
EL075_RS03880806596..807240-645WP_002466781.1HD domain-containing protein-
EL075_RS03885807368..808852-1485WP_002466786.1cardiolipin synthase-
EL075_RS03890809041..809334+294WP_002466760.1copper-sensing transcriptional repressor CsoRAntitoxin
EL075_RS03895809345..809551+207WP_002466743.1heavy-metal-associated domain-containing proteinToxin
EL075_RS03900809690..809827+138WP_002466770.1hypothetical protein-
EL075_RS03905809967..811157-1191WP_002466775.1rod shape-determining protein RodA-
EL075_RS03910811515..812585+1071WP_002466764.1D-alanine--D-alanine ligase-
EL075_RS03915812601..813962+1362WP_002466757.1UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 69 a.a.        Molecular weight: 7670.62 Da        Isoelectric Point: 3.8601

>T287351 WP_002466743.1 NZ_LR134244:809345-809551 [Staphylococcus warneri]
VQQKIVYTAGIETQEQSEAIKNLLTEMIGVYQVDIDINSGNITIEFETPANLNSIEKEIYDAGYKVLY

Download         Length: 207 bp


Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11199.74 Da        Isoelectric Point: 6.3263

>AT287351 WP_002466760.1 NZ_LR134244:809041-809334 [Staphylococcus warneri]
VTEQDHAHHSEQIKVNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVATKLLEQHMKSCIADKVNQGHQ
EEAMEELLVTFQKLMKD

Download         Length: 294 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A364UNH7


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A364UNN3

References