Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 2223136..2223662 Replicon chromosome
Accession NZ_LR134239
Organism Escherichia coli strain NCTC9100

Toxin (Protein)


Gene name relE Uniprot ID S1EXL1
Locus tag EL124_RS10825 Protein ID WP_000323025.1
Coordinates 2223375..2223662 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S1F6D3
Locus tag EL124_RS10820 Protein ID WP_000534858.1
Coordinates 2223136..2223375 (+) Length 80 a.a.

Genomic Context


ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
No matching records found

Associated MGEs


Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--2201590..223941537825


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 11225.22 Da        Isoelectric Point: 10.1967

>T287316 WP_000323025.1 NZ_LR134239:2223375-2223662 [Escherichia coli]
MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGK
RERSEVYSEAVKRIL

Download         Length: 288 bp


Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9071.48 Da        Isoelectric Point: 4.5230

>AT287316 WP_000534858.1 NZ_LR134239:2223136-2223375 [Escherichia coli]
MGSINLRIDDELKARSYAALEKMGVTPSEALRLMLEYIADNERLPFKQTLLSDEDAELVEIVKERLRNPKPVRVTLDEL

Download         Length: 240 bp


Similar Proteins


Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

Loading, please wait
Source
ID
Structure
PDB4V7K
PDB4V7J
PDB4FXI
PDB4FXE
PDB2KC8
PDB4FXH
PDB2KC9


Antitoxin

Loading, please wait
Source
ID
Structure
PDB4FXE
PDB2KC8
PDB2K29
AlphaFold DBA0A4V1CTS8

References