Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4584723..4584867 Replicon chromosome
Accession NZ_LR134235
Organism Klebsiella variicola strain NCTC9668

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4584759..4584861 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4584723..4584867 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL159_RS22675 4579852..4581913 + 2062 Protein_4276 oligopeptidase B -
EL159_RS22680 4581917..4582576 - 660 WP_008804267.1 exodeoxyribonuclease X -
EL159_RS22685 4582655..4582885 - 231 WP_012541260.1 DNA polymerase III subunit theta -
EL159_RS22690 4582999..4583373 + 375 WP_008804269.1 CopC domain-containing protein YobA -
EL159_RS22695 4583377..4584246 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
EL159_RS22700 4584263..4584601 + 339 WP_008804271.1 YebY family protein -
- 4584723..4584867 - 145 - - Antitoxin
- 4584759..4584861 + 103 - - Toxin
EL159_RS28650 4585246..4585389 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
EL159_RS22710 4585493..4586461 - 969 WP_162493241.1 VirK/YbjX family protein -
EL159_RS22715 4586617..4587270 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
EL159_RS22720 4587267..4587458 - 192 WP_002911395.1 YebW family protein -
EL159_RS22725 4587556..4587795 - 240 WP_002911393.1 YebV family protein -
EL159_RS22730 4587911..4589344 - 1434 WP_110209367.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T287255 NZ_LR134235:4584759-4584861 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT287255 NZ_LR134235:c4584867-4584723 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References