Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1059091..1059362 Replicon chromosome
Accession NZ_LR134234
Organism Escherichia coli strain NCTC8623

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1059129..1059232 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1059091..1059362 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL131_RS05220 1056248..1057687 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EL131_RS05225 1057805..1058041 + 237 WP_001295499.1 DUF1480 family protein -
EL131_RS05230 1058146..1058337 + 192 WP_000457842.1 YebW family protein -
EL131_RS05235 1058338..1058994 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 1059091..1059362 + 272 - - Antitoxin
- 1059129..1059232 - 104 - - Toxin
EL131_RS05240 1059390..1059731 - 342 WP_000976472.1 YebY family protein -
EL131_RS05245 1059744..1060616 - 873 WP_000879282.1 copper homeostasis membrane protein CopD -
EL131_RS05250 1060620..1060994 - 375 WP_000204699.1 CopC domain-containing protein YobA -
EL131_RS05255 1061133..1061363 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EL131_RS05260 1061465..1062121 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EL131_RS05265 1062145..1062807 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T287232 NZ_LR134234:c1059232-1059129 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT287232 NZ_LR134234:1059091-1059362 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References