287112

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2021568..2021839 Replicon chromosome
Accession NZ_LR134220
Organism Escherichia coli strain NCTC11121

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2021698..2021801 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2021568..2021839 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL088_RS09845 2018123..2018785 - 663 WP_000944258.1 exodeoxyribonuclease X -
EL088_RS09850 2018809..2019465 - 657 WP_073544597.1 carbon-nitrogen hydrolase family protein -
EL088_RS09855 2019567..2019797 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EL088_RS09860 2019936..2020310 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EL088_RS09865 2020314..2021186 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
EL088_RS09870 2021199..2021540 + 342 WP_000976472.1 YebY family protein -
- 2021568..2021839 - 272 - - Antitoxin
- 2021698..2021801 + 104 - - Toxin
EL088_RS09875 2021936..2022592 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
EL088_RS09880 2022593..2022784 - 192 WP_001338167.1 YebW family protein -
EL088_RS09885 2022889..2023125 - 237 WP_001338166.1 DUF1480 family protein -
EL088_RS09890 2023243..2024682 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T287112 NZ_LR134220:2021698-2021801 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT287112 NZ_LR134220:c2021839-2021568 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References