Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 704581..705244 Replicon chromosome
Accession NZ_LR134215
Organism Shimwellia blattae strain NCTC12127

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EL083_RS03375 Protein ID WP_002444974.1
Coordinates 704828..705244 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID I2B5K8
Locus tag EL083_RS03370 Protein ID WP_002444972.1
Coordinates 704581..704847 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL083_RS03350 700413..701000 + 588 WP_002444964.1 HD domain-containing protein -
EL083_RS03355 701039..701767 + 729 WP_014715822.1 MurR/RpiR family transcriptional regulator -
EL083_RS03360 701903..703336 + 1434 WP_002444968.1 6-phospho-beta-glucosidase -
EL083_RS03365 703369..704358 - 990 WP_002444970.1 tRNA-modifying protein YgfZ -
EL083_RS03370 704581..704847 + 267 WP_002444972.1 FAD assembly factor SdhE Antitoxin
EL083_RS03375 704828..705244 + 417 WP_002444974.1 hypothetical protein Toxin
EL083_RS03380 705259..705780 - 522 WP_002444975.1 flavodoxin FldB -
EL083_RS03385 705881..706801 + 921 WP_002444977.1 site-specific tyrosine recombinase XerD -
EL083_RS03390 706831..707547 + 717 WP_002444979.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
EL083_RS03395 707551..709284 + 1734 WP_002444982.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16236.11 Da        Isoelectric Point: 11.2011

>T287075 WP_002444974.1 NZ_LR134215:704828-705244 [Shimwellia blattae]
VVLWQSELRVSWRAQWLSLLLHGIVAAVVLLLPWPLNYLPVWLLLLSLVVLDCVRSQRRINARHGEIKLLDNSQLHWLGR
DWLILGTPWMSRAGMLLRLRDTTTARRHLLWVASDSVDQGEWRDLRRVLAEQKYQPPH

Download         Length: 417 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10390.84 Da        Isoelectric Point: 5.9602

>AT287075 WP_002444972.1 NZ_LR134215:704581-704847 [Shimwellia blattae]
MDINNKARIHWACRRGMRELDISIMPFFEHDYDTLSDDEKHTFVRLLACDDPDLFNWLMNHGKPADADLQHMIALIQQRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I2B5K8

References