Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2823076..2823740 Replicon chromosome
Accession NC_020059
Organism Rhizobium tropici CIAT 899

Toxin (Protein)


Gene name vapC Uniprot ID A0A5F1S0V2
Locus tag RTCIAT899_RS13930 Protein ID WP_015340881.1
Coordinates 2823330..2823740 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapC Uniprot ID A0A5F1S5Z4
Locus tag RTCIAT899_RS13925 Protein ID WP_015340880.1
Coordinates 2823076..2823330 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RTCIAT899_RS33085 2818443..2818547 - 105 Protein_2740 SAM-dependent methyltransferase -
RTCIAT899_RS13895 2818720..2819226 - 507 WP_015340874.1 VOC family protein -
RTCIAT899_RS13900 2819226..2819615 - 390 WP_015340875.1 RidA family protein -
RTCIAT899_RS13905 2819677..2820573 - 897 WP_041677957.1 DMT family transporter -
RTCIAT899_RS13910 2820819..2821244 + 426 WP_015340877.1 hypothetical protein -
RTCIAT899_RS13915 2821296..2821907 - 612 WP_015340878.1 alpha/beta hydrolase -
RTCIAT899_RS13920 2821923..2822855 - 933 WP_015340879.1 VOC family protein -
RTCIAT899_RS13925 2823076..2823330 + 255 WP_015340880.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
RTCIAT899_RS13930 2823330..2823740 + 411 WP_015340881.1 type II toxin-antitoxin system VapC family toxin Toxin
RTCIAT899_RS13935 2823734..2824435 - 702 WP_015340882.1 uracil-DNA glycosylase -
RTCIAT899_RS13940 2824664..2825203 + 540 WP_015340883.1 adenylate kinase -
RTCIAT899_RS13945 2825249..2827696 - 2448 WP_015340884.1 FAD-dependent oxidoreductase -
RTCIAT899_RS13950 2827706..2828584 - 879 WP_015340885.1 phosphotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-117)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-63)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15298.36 Da        Isoelectric Point: 6.8812

>T28707 WP_015340881.1 NC_020059:2823330-2823740 [Rhizobium tropici CIAT 899]
MYLVDTNVISEIRRGNSQAIDWLRSVDPSTIYLSVITLGEIMRGIALKRKSDPRTATHLEGWLRKLRHDHRNRILPITDQ
IAVEWGRIAAQRPRGDADGLIAATAIVHDLIVVTRDVGDFDDTGASISNPWDQTPY

Download         Length: 411 bp

>T28707 NC_020059:2823330-2823740 [Rhizobium tropici CIAT 899]
ATGTACCTCGTCGATACCAACGTCATCTCGGAAATCCGGCGCGGTAATTCCCAAGCGATTGACTGGCTGCGCTCGGTCGA
TCCCTCCACCATCTATCTGAGCGTCATCACACTTGGAGAGATCATGCGCGGGATTGCGCTCAAGCGAAAATCGGACCCGC
GTACCGCAACACATCTGGAGGGATGGTTGCGTAAGCTGCGGCACGATCATCGCAATCGCATCCTTCCCATTACCGATCAG
ATTGCCGTCGAATGGGGCCGCATCGCGGCACAGCGCCCGCGCGGCGACGCCGACGGTTTGATCGCGGCAACGGCGATCGT
TCATGATCTTATCGTCGTCACCCGCGACGTCGGAGATTTCGACGACACGGGCGCTTCGATCAGCAACCCATGGGACCAGA
CACCTTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9205.30 Da        Isoelectric Point: 4.5105

>AT28707 WP_015340880.1 NC_020059:2823076-2823330 [Rhizobium tropici CIAT 899]
MNWPLQDAKNQFSKVVQKARSEGPQIVTLRGERAAVVLSAEDYDALSAGKPSLVDDLLSGPAWDDEMTDAVSNRSKTPSR
DILF

Download         Length: 255 bp

>AT28707 NC_020059:2823076-2823330 [Rhizobium tropici CIAT 899]
ATGAATTGGCCGCTGCAGGATGCGAAGAACCAGTTTTCAAAAGTCGTGCAGAAAGCGCGCAGCGAGGGACCGCAAATCGT
CACCTTGCGCGGCGAACGTGCGGCTGTCGTCCTATCTGCCGAAGATTATGATGCCCTCTCAGCCGGCAAACCAAGCCTCG
TCGACGATCTGCTATCCGGACCGGCATGGGATGACGAAATGACTGATGCCGTATCGAACCGCAGCAAAACGCCGAGCCGA
GATATCCTCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5F1S0V2

Antitoxin

Source ID Structure
AlphaFold DB A0A5F1S5Z4

References