Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1007394..1007950 Replicon chromosome
Accession NZ_LR134201
Organism Cedecea lapagei strain NCTC11466

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag EL098_RS04980 Protein ID WP_126355253.1
Coordinates 1007394..1007705 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag EL098_RS04985 Protein ID WP_126355254.1
Coordinates 1007708..1007950 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL098_RS04960 1003174..1004640 + 1467 WP_126355250.1 IMP dehydrogenase -
EL098_RS04965 1004708..1006285 + 1578 WP_045783526.1 glutamine-hydrolyzing GMP synthase -
EL098_RS04970 1006548..1006781 + 234 WP_126355251.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
EL098_RS04975 1006812..1007144 + 333 WP_126355252.1 type II toxin-antitoxin system RelE/ParE family toxin -
EL098_RS04980 1007394..1007705 - 312 WP_126355253.1 CcdB family protein Toxin
EL098_RS04985 1007708..1007950 - 243 WP_126355254.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
EL098_RS04990 1008164..1009369 + 1206 WP_126355255.1 M24 family metallopeptidase -
EL098_RS04995 1009411..1010028 - 618 WP_126355256.1 LysE family transporter -
EL098_RS05000 1010213..1011133 + 921 WP_126355257.1 LysR family transcriptional regulator -
EL098_RS05005 1011127..1012143 - 1017 WP_126355258.1 LD-carboxypeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(10-80)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11564.26 Da        Isoelectric Point: 7.1614

>T287014 WP_126355253.1 NZ_LR134201:c1007705-1007394 [Cedecea lapagei]
MQFTVYKNTGKPTAYPYLLNVQSNIIGRRNTRVVIPLFPAENYKGPRTDKLTPSINLAGEDFIVMTHELASIPERVLGAE
HCSAAEYENTIKAALNFLFYGIE

Download         Length: 312 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8934.18 Da        Isoelectric Point: 5.1106

>AT287014 WP_126355254.1 NZ_LR134201:c1007950-1007708 [Cedecea lapagei]
MPASASIRVKKTVTVTLEPDLIQEAKAAGINLSQTLRNALKAEIKEIEAARWKKENEAAIDYLNQLTEENGLLSDTYRTF

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References