Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) KacT-ataR/DUF1778(antitoxin)
Location 831603..832400 Replicon chromosome
Accession NZ_LR134201
Organism Cedecea lapagei strain NCTC11466

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag EL098_RS04195 Protein ID WP_126355027.1
Coordinates 831876..832400 (+) Length 175 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EL098_RS04190 Protein ID WP_126355025.1
Coordinates 831603..831872 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL098_RS04160 827108..827788 + 681 WP_126355014.1 nitroreductase -
EL098_RS04165 827785..828651 - 867 WP_126355016.1 EamA family transporter -
EL098_RS04170 828744..829529 + 786 WP_126355018.1 helix-turn-helix transcriptional regulator -
EL098_RS04175 829601..829936 - 336 WP_126355020.1 hypothetical protein -
EL098_RS04180 830086..830391 - 306 WP_126355022.1 chaperone modulator CbpM -
EL098_RS04185 830391..831311 - 921 WP_126355023.1 curved DNA-binding protein -
EL098_RS04190 831603..831872 + 270 WP_126355025.1 DUF1778 domain-containing protein Antitoxin
EL098_RS04195 831876..832400 + 525 WP_126355027.1 GNAT family N-acetyltransferase Toxin
EL098_RS04200 832574..833158 + 585 WP_126355029.1 hypothetical protein -
EL098_RS04205 833451..833930 + 480 WP_126355031.1 Rrf2 family transcriptional regulator -
EL098_RS04210 834033..837185 - 3153 WP_126355033.1 multidrug efflux RND transporter permease subunit OqxB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(81-150)

Antitoxin

Vibrio phage ICP1, Orf50

(3-87)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19402.13 Da        Isoelectric Point: 7.7633

>T287013 WP_126355027.1 NZ_LR134201:831876-832400 [Cedecea lapagei]
VADLTIELFSADTAYDFCGFDCGDTCLNAFLAEHFIRQHNGRFLRGYLLVTKDANPKVLGYYTLSGSCFEKETLPSNSQK
RKIPYANVPSVTLGRLAIHKDLQGQEWGSTLVAHAMKVVYLASQAVGVHGIFVDAINDNAKRFYQKLGFITLVGKNANSL
FYPTRSIETLFEHQ

Download         Length: 525 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10117.59 Da        Isoelectric Point: 5.8581

>AT287013 WP_126355025.1 NZ_LR134201:831603-831872 [Cedecea lapagei]
MSALKKQRIDLRLSDDDKSMIEEAAAMSNQTITQFMIACASARAAEVIEQHRRLVLNEASWNRVMDAISNPPEPDDRLKR
AARCLKDME

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References