287012

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 615983..616652 Replicon chromosome
Accession NZ_LR134201
Organism Cedecea lapagei strain NCTC11466

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EL098_RS03155 Protein ID WP_126354697.1
Coordinates 616230..616652 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag EL098_RS03150 Protein ID WP_126354695.1
Coordinates 615983..616249 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL098_RS03130 612501..613229 - 729 WP_126354687.1 MurR/RpiR family transcriptional regulator -
EL098_RS03135 613272..613865 - 594 WP_126354689.1 HD domain-containing protein -
EL098_RS03140 614045..614698 + 654 WP_126354691.1 hemolysin III family protein -
EL098_RS03145 614750..615736 - 987 WP_126354693.1 tRNA-modifying protein YgfZ -
EL098_RS03150 615983..616249 + 267 WP_126354695.1 FAD assembly factor SdhE Antitoxin
EL098_RS03155 616230..616652 + 423 WP_126354697.1 protein YgfX Toxin
EL098_RS03160 616649..617170 - 522 WP_126354699.1 flavodoxin FldB -
EL098_RS03165 617273..618169 + 897 WP_126354701.1 site-specific tyrosine recombinase XerD -
EL098_RS03170 618196..618912 + 717 WP_126354703.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
EL098_RS03175 618919..620652 + 1734 WP_126354705.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 141 a.a.        Molecular weight: 16491.50 Da        Isoelectric Point: 11.4781

>T287012 WP_126354697.1 NZ_LR134201:616230-616652 [Cedecea lapagei]
VVLWQSDLRVSWRAQWMSLLLHGMVALLVLLMPWPMSYTLIWMLLLSLVVFDSVRSQRRIHARQGEIKLLTDCRLRWQGR
EWDIVGNPWLIDSGAMLRLRRAGKQRCQHLWLAADSMDIGEWRDLRRLLMQQQASGSGQI

Download         Length: 423 bp


Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10374.85 Da        Isoelectric Point: 5.6202

>AT287012 WP_126354695.1 NZ_LR134201:615983-616249 [Cedecea lapagei]
MDINNKARIHWACRRGMRELDISIMPFFEHEYETLSDSDKALFVRLLESDDPDLFNWLMNHGKPADTELQRMVSLIQTRN
KERGPVAI

Download         Length: 267 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References