Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 2725078..2725829 Replicon chromosome
Accession NZ_LR134195
Organism Raoultella ornithinolytica strain NCTC13096

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag EL106_RS12900 Protein ID WP_126509690.1
Coordinates 2725347..2725829 (+) Length 161 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A808Y4Y8
Locus tag EL106_RS12895 Protein ID WP_015584326.1
Coordinates 2725078..2725356 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL106_RS12885 2721867..2722364 + 498 WP_048023692.1 hypothetical protein -
EL106_RS12890 2722522..2724447 - 1926 WP_126509688.1 C1 family peptidase -
EL106_RS12895 2725078..2725356 + 279 WP_015584326.1 DUF1778 domain-containing protein Antitoxin
EL106_RS12900 2725347..2725829 + 483 WP_126509690.1 GNAT family N-acetyltransferase Toxin
EL106_RS25855 2726014..2726364 + 351 WP_044351090.1 hypothetical protein -
EL106_RS12910 2726652..2727989 - 1338 WP_126509692.1 hypothetical protein -
EL106_RS12915 2728016..2728699 - 684 WP_126509693.1 hypothetical protein -
EL106_RS12920 2728869..2729006 + 138 Protein_2493 transposase -
EL106_RS12925 2729397..2729786 + 390 WP_126509695.1 hypothetical protein -
EL106_RS12930 2729752..2730099 + 348 WP_126509697.1 hypothetical protein -
EL106_RS25920 2730238..2730756 + 519 WP_197719528.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2722522..2734930 12408


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-144)

Antitoxin

Vibrio phage ICP1, Orf50

(3-92)


Sequences

Toxin        


Download         Length: 161 a.a.        Molecular weight: 17616.47 Da        Isoelectric Point: 9.7381

>T286998 WP_126509690.1 NZ_LR134195:2725347-2725829 [Raoultella ornithinolytica]
MGMRPPEPLSAGHNIAEFCCQDQVLNEWLKKKALKNHSTGISRVFVVCAENTKRVIAYYSLSSGSVHRNTVTGAYRRNAP
EAVPVIVLGRLAVDAAWAGKGLGAALLKDAIYRTEHIAVQVGVRALLVHALNDEVREFYTRFGFEPSIINTLTLLFPIKV

Download         Length: 483 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10714.30 Da        Isoelectric Point: 4.6722

>AT286998 WP_015584326.1 NZ_LR134195:2725078-2725356 [Raoultella ornithinolytica]
MKPDVREAPINIRAKTSQRDLIDMAANLVSKSRTDFMLEVACREAQDILLDQRLFLLDDKQFASFMEELDAPMTAERQAR
IDNLMNRKSPWE

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A808Y4Y8

References