Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2395340..2396253 Replicon chromosome
Accession NZ_LR134195
Organism Raoultella ornithinolytica strain NCTC13096

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag EL106_RS11235 Protein ID WP_069475889.1
Coordinates 2395340..2395813 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A808Y7A4
Locus tag EL106_RS11240 Protein ID WP_004862777.1
Coordinates 2395810..2396253 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL106_RS11210 2391379..2391987 - 609 WP_044349854.1 glutathione S-transferase family protein -
EL106_RS11215 2392229..2393134 + 906 WP_032716408.1 transcriptional regulator GcvA -
EL106_RS11220 2393162..2394067 - 906 WP_126509578.1 LysR family transcriptional regulator -
EL106_RS11225 2394170..2394487 + 318 WP_126509579.1 nuclear transport factor 2 family protein -
EL106_RS11230 2394480..2395259 + 780 WP_118860327.1 SDR family oxidoreductase -
EL106_RS11235 2395340..2395813 - 474 WP_069475889.1 RES domain-containing protein Toxin
EL106_RS11240 2395810..2396253 - 444 WP_004862777.1 DUF2384 domain-containing protein Antitoxin
EL106_RS11245 2398824..2399390 - 567 WP_126509581.1 DJ-1/PfpI family protein -
EL106_RS11250 2399985..2400968 + 984 WP_126509583.1 type I-F CRISPR-associated endonuclease Cas1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17540.86 Da        Isoelectric Point: 4.8081

>T286997 WP_069475889.1 NZ_LR134195:c2395813-2395340 [Raoultella ornithinolytica]
MIFYRLVTGRYASEAWTGSGANQYGGRWNHQGHPAVYVSTSIALASLEILVHVKNEAILNQYQLYSIEIPDSEVESLDKQ
WLPDNWQENPMPVSTMDLGTGWLQSGSGLALMLPSCIIPYENNAILNPLHPAFSEALASVRQYPFTFDPRLARSTLL

Download         Length: 474 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16190.45 Da        Isoelectric Point: 4.9405

>AT286997 WP_004862777.1 NZ_LR134195:c2396253-2395810 [Raoultella ornithinolytica]
MKTWVPAEQPADNALWRYAGLPANRGMQLIELLSMGLPVSILDNIHEWTEMSKTDILRITGINERNVARRKSAGGTLTPG
ESERVARFVRVLDTAVDYFGSKQDAYDWLQSPVRGLGNVAPIDLIATESGALEVTDLIGRLEHGVFA

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A808Y7A4

References