Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 872220..872877 Replicon chromosome
Accession NZ_LR134195
Organism Raoultella ornithinolytica strain NCTC13096

Toxin (Protein)


Gene name cptA Uniprot ID A0A808XTM6
Locus tag EL106_RS04225 Protein ID WP_004867355.1
Coordinates 872467..872877 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A514ELX1
Locus tag EL106_RS04220 Protein ID WP_004867358.1
Coordinates 872220..872486 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL106_RS04195 867355..868788 - 1434 WP_086815888.1 6-phospho-beta-glucosidase -
EL106_RS04200 868908..869636 - 729 WP_004867368.1 MurR/RpiR family transcriptional regulator -
EL106_RS04205 869686..869997 + 312 WP_004867365.1 N(4)-acetylcytidine aminohydrolase -
EL106_RS04210 870159..870818 + 660 WP_004867362.1 hemolysin III family protein -
EL106_RS04215 870940..871923 - 984 WP_015585783.1 tRNA-modifying protein YgfZ -
EL106_RS04220 872220..872486 + 267 WP_004867358.1 FAD assembly factor SdhE Antitoxin
EL106_RS04225 872467..872877 + 411 WP_004867355.1 protein YgfX Toxin
EL106_RS04230 872892..873407 - 516 Protein_822 flavodoxin FldB -
EL106_RS04235 873585..874481 + 897 WP_015585784.1 site-specific tyrosine recombinase XerD -
EL106_RS04240 874523..875218 + 696 WP_126509392.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
EL106_RS04245 875224..876956 + 1733 Protein_825 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16226.16 Da        Isoelectric Point: 11.3349

>T286992 WP_004867355.1 NZ_LR134195:872467-872877 [Raoultella ornithinolytica]
VVLWQSDLRISWRSQWFSLLLHGIVAAIVLLMPWPLSYTPLWLLLLSLVVFDSVRSQRRIHACRGEIKLMTDSRLRWQKA
EWEIVGTPWVINSGMLLRLQDMQTRRRQHLWIAADSMDAKEWRDLRRLVLQKPAQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10553.05 Da        Isoelectric Point: 4.8432

>AT286992 WP_004867358.1 NZ_LR134195:872220-872486 [Raoultella ornithinolytica]
MDITNKARIHWACRRGMRELDISIMPFFEYEYDTLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADAQLQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808XTM6

Antitoxin

Source ID Structure
AlphaFold DB A0A514ELX1

References