Detailed information of TA system TA286967

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): sdenTA/AbiEii(toxin)
• Location: 1119327..1120757
• Replicon: chromosome
• Accession: NZ_LR134189
• Organism: Providencia rustigianii strain NCTC6933

Toxin (Protein)

• Gene name: sdenT
• Uniprot ID: -
• Locus tag: EL059_RS05095
• Protein ID: WP_126436475.1
• Coordinates: 1119327..1120217 (-)
• Length: 297 a.a.

Antitoxin (Protein)

• Gene name: sdenA
• Uniprot ID: D1NXR7
• Locus tag: EL059_RS05100
• Protein ID: WP_006812791.1
• Coordinates: 1120233..1120757 (-)
• Length: 175 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL059_RS05070	1114654..1115349	+	696	WP_126436473.1	hypothetical protein	-
EL059_RS05075	1115360..1115614	+	255	WP_115164053.1	cloacin	-
EL059_RS05080	1115703..1116197	-	495	WP_006812795.1	DUF2569 domain-containing protein	-
EL059_RS05085	1116438..1117253	+	816	WP_006812794.1	sulfite exporter TauE/SafE family protein	-
EL059_RS05090	1117401..1119068	+	1668	WP_039854007.1	glutamine--tRNA ligase	-
EL059_RS05095	1119327..1120217	-	891	WP_126436475.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
EL059_RS05100	1120233..1120757	-	525	WP_006812791.1	hypothetical protein	Antitoxin
EL059_RS05105	1120932..1121327	-	396	WP_115164056.1	DUF5329 family protein	-
EL059_RS05110	1121438..1122121	-	684	WP_006812789.1	two-component system response regulator KdpE	-
EL059_RS05115	1122138..1124831	-	2694	WP_112836366.1	two-component system sensor histidine kinase KdpD	-
EL059_RS05120	1124840..1125433	-	594	WP_039854006.1	potassium-transporting ATPase subunit KdpC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (36-267)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 297 a.a.
• Molecular weight: 34537.73 Da
• Isoelectric Point: 6.1750

>T286967 WP_126436475.1 NZ_LR134189:c1120217-1119327 [Providencia rustigianii]
MLKQQIRQIIQVNPDYAAITPVIEKEILHHDIMDVLIRQGAMQRLTFIGGTSLRMCYNSSRLSEDLDFNGGHDFKPTEFD
GLEFEIQKYIQNKYETDVWVNKPSEEKQGDTVSWKISIVKEANRPDLPRQKMHIDVCAIPSFDIEKRPLLNHYDIVVPTE
GILVPVQSLQETLADKLIALAYRARRIKPRDIWDIVWIKQRGISLSKTLVEKKLIARNKEIDDFHHAIAIQLNKLMQEDD
LRNDFNAEMSRFIPKQIKERTVDNPEYWAYVQTEVNDIVTELLNNIKPKNPFDMGL

Nucleotide

• Length: 891 bp

Antitoxin

Protein

• Length: 175 a.a.
• Molecular weight: 19427.73 Da
• Isoelectric Point: 10.0491

>AT286967 WP_006812791.1 NZ_LR134189:c1120757-1120233 [Providencia rustigianii]
MAKIDKLLSALASAVKAGGGIHSAAELAFMLGEPCNPTFRKFLTDSVKKGQLRRVVKGLYESVLTPPEPETAIYKIIKKL
RSNVLNYISLESQLSYTGNISQVIMGRVTVITKGRSGRFDTPYGVIEFIHTKKPIEQIAPNLYYDSDIKMYRANTAQAII
DLKHCQRNIHMLDL

Nucleotide

• Length: 525 bp

Structures

Antitoxin

• AlphaFold DB: A0A379G1B1