286961

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2674845..2675382 Replicon chromosome
Accession NZ_LR134176
Organism Legionella pneumophila strain NCTC12179

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL037_RS12060 Protein ID WP_027266055.1
Coordinates 2674845..2675141 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL037_RS12065 Protein ID WP_027266056.1
Coordinates 2675131..2675382 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL037_RS12030 (NCTC12179_02538) 2670937..2671833 - 897 WP_027266053.1 hypothetical protein -
EL037_RS12035 (NCTC12179_02539) 2672101..2672292 + 192 WP_014327021.1 hypothetical protein -
EL037_RS12040 2672441..2672545 - 105 Protein_2393 lytic murein transglycosylase -
EL037_RS12045 (NCTC12179_02540) 2672763..2673302 - 540 WP_062730332.1 tetratricopeptide repeat protein -
EL037_RS12050 (NCTC12179_02541) 2673262..2673915 - 654 WP_027266054.1 hypothetical protein -
EL037_RS12055 (NCTC12179_02542) 2674274..2674756 - 483 WP_014842908.1 hypothetical protein -
EL037_RS12060 (NCTC12179_02543) 2674845..2675141 - 297 WP_027266055.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL037_RS12065 (NCTC12179_02544) 2675131..2675382 - 252 WP_027266056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EL037_RS12070 (NCTC12179_02545) 2675546..2676751 + 1206 WP_061638482.1 ISNCY family transposase -
EL037_RS16670 2676924..2677124 - 201 WP_027265577.1 hypothetical protein -
EL037_RS12080 (NCTC12179_02546) 2677702..2678841 - 1140 WP_134984249.1 DUF3800 domain-containing protein -
EL037_RS16675 2678959..2679066 - 108 WP_229310140.1 hypothetical protein -
EL037_RS16680 2679172..2679503 - 332 Protein_2403 recombinase family protein -
EL037_RS16200 2679591..2679731 + 141 WP_154219844.1 hypothetical protein -
EL037_RS12090 (NCTC12179_02549) 2679756..2680259 - 504 WP_027265579.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-60)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11512.36 Da        Isoelectric Point: 10.3916

>T286961 WP_027266055.1 NZ_LR134176:c2675141-2674845 [Legionella pneumophila]
MIYELHFHPLALKEWKKLGKNLQEEFKKVLKRRLENPHVASASLRGSLKNCYKIKLRQSGYRLVYQVNDNKLIVTVIAVG
KRNKNVVYDDADNRQEDS

Download         Length: 297 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9271.70 Da        Isoelectric Point: 5.0359

>AT286961 WP_027266056.1 NZ_LR134176:c2675382-2675131 [Legionella pneumophila]
MQTLFATQVASISELKKNPTKLINDAHGKPVAILNHNTAAAYLIPVETFEKLMDLIDENELHKIVEERLSAPFTSIKVNI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References