Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1996427..1996988 Replicon chromosome
Accession NZ_LR134167
Organism Avibacterium volantium strain NCTC3438

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ELZ61_RS09430 Protein ID WP_126373185.1
Coordinates 1996659..1996988 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ELZ61_RS09425 Protein ID WP_126373183.1
Coordinates 1996427..1996669 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ61_RS09405 1991685..1992527 + 843 WP_035686885.1 ABC transporter permease -
ELZ61_RS09410 1992551..1993633 + 1083 WP_126373671.1 extracellular solute-binding protein -
ELZ61_RS09415 1993819..1995129 + 1311 WP_126373179.1 histidine-type phosphatase -
ELZ61_RS09420 1995222..1996307 + 1086 WP_126373181.1 ROK family protein -
ELZ61_RS09425 1996427..1996669 + 243 WP_126373183.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
ELZ61_RS09430 1996659..1996988 + 330 WP_126373185.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ELZ61_RS09435 1996992..1997558 - 567 WP_103853318.1 elongation factor P -
ELZ61_RS09440 1997593..1998606 + 1014 WP_126373187.1 EF-P beta-lysylation protein EpmB -
ELZ61_RS09445 1998700..1999920 + 1221 WP_126373189.1 opacity-associated protein OapA -
ELZ61_RS09450 2000009..2000914 - 906 WP_126373191.1 recombination-associated protein RdgC -
ELZ61_RS09455 2000985..2001800 + 816 WP_126373193.1 pyrroline-5-carboxylate reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-76)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13027.23 Da        Isoelectric Point: 10.2293

>T286941 WP_126373185.1 NZ_LR134167:1996659-1996988 [Avibacterium volantium]
MNYELVFDPRALKEWRKLDENIKAQFKKKLAEILRNPHIEANRLSHFPDCYKIKLRNAGYRLIYQVQDEQVIVFVVAIGK
QENNQAYKEAKKSYKKSVLLYGFFVFALR

Download         Length: 330 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9237.60 Da        Isoelectric Point: 4.7769

>AT286941 WP_126373183.1 NZ_LR134167:1996427-1996669 [Avibacterium volantium]
MATLNIRLDDELKQEAYAALQKMNLTPSEAVRLLFQYVAQNNKFPIQTVLVNDEDLELLETVRHRLAHPEKGIKVSFDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References