Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 562057..562687 Replicon chromosome
Accession NZ_LR134167
Organism Avibacterium volantium strain NCTC3438

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ELZ61_RS02750 Protein ID WP_126371256.1
Coordinates 562361..562687 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ELZ61_RS02745 Protein ID WP_126371254.1
Coordinates 562057..562380 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ61_RS02720 557665..558126 - 462 WP_115248572.1 DMT family transporter -
ELZ61_RS02725 558230..558898 - 669 WP_126371248.1 NAD(P)H-dependent oxidoreductase -
ELZ61_RS02730 559040..560353 - 1314 WP_126371250.1 anaerobic C4-dicarboxylate transporter -
ELZ61_RS02735 560631..561077 + 447 WP_126371252.1 rhodanese-like domain-containing protein -
ELZ61_RS02740 561096..561602 + 507 WP_103855395.1 protein-export chaperone SecB -
ELZ61_RS02745 562057..562380 - 324 WP_126371254.1 putative addiction module antidote protein Antitoxin
ELZ61_RS02750 562361..562687 - 327 WP_126371256.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ELZ61_RS02755 562892..563905 + 1014 WP_126371258.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
ELZ61_RS02760 563907..564704 + 798 WP_126371260.1 serine O-acetyltransferase -
ELZ61_RS02765 564714..565529 + 816 WP_126371262.1 shikimate 5-dehydrogenase -
ELZ61_RS02770 565597..567456 - 1860 WP_126371265.1 selenocysteine-specific translation elongation factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-98)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-100)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12275.23 Da        Isoelectric Point: 10.2562

>T286937 WP_126371256.1 NZ_LR134167:c562687-562361 [Avibacterium volantium]
MNEIILTDEFRLWLTKLKNPIAKATIARRIKNAIKGNFGDHKPLAGANGIYEMRIATGAGYRVYYVQQGKVVYVLLCGGD
KSTQKNDIERAKQLFNVLQRGENEINKY

Download         Length: 327 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11949.71 Da        Isoelectric Point: 4.7283

>AT286937 WP_126371254.1 NZ_LR134167:c562380-562057 [Avibacterium volantium]
MKSTNINEAAIDALGLKPFDVAEYLNDEETIQAYLMEVLKEGNQDEFLEALSDVARARGMTELAKQTGLGRESLYKTLSK
GSKPRFETIQKILAAFNLELVPTIKVR

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References