286933

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3690163..3690820 Replicon chromosome
Accession NZ_LR134164
Organism Enterobacter hormaechei strain NCTC11571

Toxin (Protein)


Gene name cptA Uniprot ID A0A0A6GSQ9
Locus tag EL051_RS17625 Protein ID WP_022649305.1
Coordinates 3690163..3690573 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag EL051_RS17630 Protein ID WP_003863437.1
Coordinates 3690554..3690820 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL051_RS17605 3686161..3687894 - 1734 WP_063163563.1 single-stranded-DNA-specific exonuclease RecJ -
EL051_RS17610 3687900..3688613 - 714 WP_022649304.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
EL051_RS17615 3688642..3689538 - 897 WP_003863442.1 site-specific tyrosine recombinase XerD -
EL051_RS17620 3689640..3690161 + 522 WP_015571793.1 flavodoxin FldB -
EL051_RS17625 3690163..3690573 - 411 WP_022649305.1 protein YgfX Toxin
EL051_RS17630 3690554..3690820 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
EL051_RS17635 3691115..3692095 + 981 WP_126315160.1 tRNA-modifying protein YgfZ -
EL051_RS17640 3692618..3693277 - 660 WP_022649307.1 hemolysin III family protein -
EL051_RS17645 3693544..3694275 + 732 WP_022649308.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T286933 WP_022649305.1 NZ_LR134164:c3690573-3690163 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAAMVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMIGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT286933 WP_003863437.1 NZ_LR134164:c3690820-3690554 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0A6GSQ9

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References