Detailed information of TA system TA286932

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yfjZ-ypjF/CbtA-CbeA
• Location: 3401861..3402519
• Replicon: chromosome
• Accession: NZ_LR134164
• Organism: Enterobacter hormaechei strain NCTC11571

Toxin (Protein)

• Gene name: ypjF
• Uniprot ID: -
• Locus tag: EL051_RS16265
• Protein ID: WP_032637385.1
• Coordinates: 3402199..3402519 (+)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: EL051_RS16260
• Protein ID: WP_126315089.1
• Coordinates: 3401861..3402178 (+)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL051_RS16220	3397421..3398254	+	834	WP_126315082.1	DUF945 domain-containing protein	-
EL051_RS16225	3398456..3399160	+	705	WP_126315083.1	WYL domain-containing protein	-
EL051_RS16230	3399157..3399771	+	615	WP_046495819.1	hypothetical protein	-
EL051_RS16235	3399860..3400270	+	411	WP_126315084.1	hypothetical protein	-
EL051_RS16240	3400348..3400584	+	237	WP_126315085.1	DUF905 domain-containing protein	-
EL051_RS16245	3400663..3401121	+	459	WP_126315086.1	antirestriction protein	-
EL051_RS16250	3401130..3401612	+	483	WP_126315087.1	DNA repair protein RadC	-
EL051_RS16255	3401621..3401842	+	222	WP_126315088.1	DUF987 domain-containing protein	-
EL051_RS16260	3401861..3402178	+	318	WP_126315089.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
EL051_RS16265	3402199..3402519	+	321	WP_032637385.1	TA system toxin CbtA family protein	Toxin
EL051_RS16270	3403102..3404340	+	1239	WP_126315090.1	ribokinase	-
EL051_RS16275	3404408..3405385	+	978	WP_126315091.1	sugar ABC transporter permease	-
EL051_RS16280	3405385..3406284	+	900	WP_126315092.1	carbohydrate ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3381344..3402519	21175

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-104)

Antitoxin

• Antitoxin CbeA (5-103)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12146.14 Da
• Isoelectric Point: 7.1656

>T286932 WP_032637385.1 NZ_LR134164:3402199-3402519 [Enterobacter hormaechei]
MKTLPATTLWAAKPCPSPVIVWQMLLSRLLDQHYGLTLNDTPFSDETVIKEHIDAGISLADAVNFLVEKYELVRIDRKGF
SWQEQSPFITAVDILKARRAMREMRT

Nucleotide

• Length: 321 bp

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11976.54 Da
• Isoelectric Point: 6.7344

>AT286932 WP_126315089.1 NZ_LR134164:3401861-3402178 [Enterobacter hormaechei]
MSNITWGLQRDITPRLGSRLVQEGNRLHYLADRASITGKFSDVECRKLDETFPHFISQMESMLTTDELNPRHAHCVTLCH
NGFTCEADTLGSCGYVYITVYPTHR

Nucleotide

• Length: 318 bp