Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 4334003..4335632 Replicon chromosome
Accession NZ_LR134161
Organism Yersinia enterocolitica subsp. enterocolitica strain NCTC13629

Toxin (Protein)


Gene name hipA Uniprot ID A0A7U7IQ60
Locus tag EL026_RS20415 Protein ID WP_005165219.1
Coordinates 4334304..4335632 (+) Length 443 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID A0A7U7FJW4
Locus tag EL026_RS20410 Protein ID WP_005165217.1
Coordinates 4334003..4334302 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(8-108)

Antitoxin

Cro/C1-type helix-turn-helix domain

(18-66)


Sequences

Toxin        


Download         Length: 443 a.a.        Molecular weight: 49925.93 Da        Isoelectric Point: 6.8736

>T286916 WP_005165219.1 NZ_LR134161:4334304-4335632 [Yersinia enterocolitica subsp. enterocolitica]
MARRIQRLNIWMNGQHVGYWEKNRGEESLVYAQEWLANEQGRPLSLSLPFTANNQVYRGNIVRDYFDNLLPDSDDIRRRL
ATKYHADSINPFDLLFELGRDCVGAIQLLTDDAPPSDLFSIQQQPLTESDVARILRNSLSDNAFVRPEHDEDLRLSIAGA
QEKTALLFHDNRWCLPLGSTPTTHIFKLPLGLVGNMQADMRTSVENEWLCAKILASYNLPVASCEIGQFEDQKALIVERF
DRRLSRDKSWIVRLPQEDMCQATGTSPLKKYQMDGGPSITTIMEILSGSDNASEDRNVFFKAQIIFWLLAATDGHAKNFS
IAHLPGSRYHLTPLYDVLSTHPIIGSGRNQIAVQKSKLAMAVRGSKNYYLINQIQRRHWRKQAEFVGLGAIQADTIIDEI
IAATPRVITQVQAQLPANFPADLAEKILTGLHKQCEKISAML

Download         Length: 1329 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11141.78 Da        Isoelectric Point: 8.5374

>AT286916 WP_005165217.1 NZ_LR134161:4334003-4334302 [Yersinia enterocolitica subsp. enterocolitica]
MDYPIKILSQLRPTLIGFRKNKGLTQASLAQLLGITQQSYAKLEADPTSASVERLFKVLQLLDVELILSEKKNASAHPNK
THQPEQSQTIDLPSKQEDW

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7IQ60

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7FJW4

References