Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ypjF-yeeU/CbtA-CbeA
Location 413956..414540 Replicon chromosome
Accession NZ_LR134161
Organism Yersinia enterocolitica subsp. enterocolitica strain NCTC13629

Toxin (Protein)


Gene name ypjF Uniprot ID A0A7U7ISC5
Locus tag EL026_RS01840 Protein ID WP_005165296.1
Coordinates 413956..414324 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag EL026_RS01845 Protein ID WP_129019424.1
Coordinates 414388..414540 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL026_RS01820 409163..410083 + 921 WP_005165286.1 ROK family protein -
EL026_RS01825 410168..411130 + 963 WP_005165289.1 LacI family transcriptional regulator -
EL026_RS01830 411164..411637 - 474 WP_005165291.1 GNAT family N-acetyltransferase -
EL026_RS01835 412873..413727 - 855 WP_005165294.1 DUF4942 domain-containing protein -
EL026_RS01840 413956..414324 - 369 WP_005165296.1 TA system toxin CbtA family protein Toxin
EL026_RS01845 414388..414540 - 153 WP_129019424.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EL026_RS01850 414609..415811 + 1203 WP_005178352.1 IS256 family transposase -
EL026_RS01855 415986..417449 + 1464 WP_005166182.1 alpha/beta hydrolase -
EL026_RS01860 417682..419088 - 1407 WP_005166180.1 filamentous hemagglutinin N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 414609..415811 1202


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(1-45)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13609.55 Da        Isoelectric Point: 6.4731

>T286903 WP_005165296.1 NZ_LR134161:c414324-413956 [Yersinia enterocolitica subsp. enterocolitica]
MQTLPVTSKRAAYACLSPVIVWQSMLTYLLEQHYGLVLSDTEFSDDAVIHEHIDAGISLADALNFTVEKFDLARTDHRGF
SCQEQSPFITSIDILRARRATGLMTRMGYQTITSVIRGGKQA

Download         Length: 369 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5593.44 Da        Isoelectric Point: 4.5803

>AT286903 WP_129019424.1 NZ_LR134161:c414540-414388 [Yersinia enterocolitica subsp. enterocolitica]
MELMLLSGELNPRYQHCVTLYRNGLICEADSLGSQGYVYLAIYPTPQSIA

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7ISC5

Antitoxin

Source ID Structure

References