Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4294990..4295659 Replicon chromosome
Accession NZ_LR134151
Organism Serratia plymuthica strain NCTC8900

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EL066_RS20485 Protein ID WP_126485007.1
Coordinates 4294990..4295412 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag EL066_RS20490 Protein ID WP_126485009.1
Coordinates 4295393..4295659 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL066_RS20465 4290873..4291390 + 518 Protein_3954 flavodoxin FldB -
EL066_RS20470 4291432..4292796 - 1365 WP_126485003.1 cell envelope integrity protein CreD -
EL066_RS20475 4292881..4294299 - 1419 WP_126485005.1 two-component system sensor histidine kinase CreC -
EL066_RS20480 4294296..4294993 - 698 Protein_3957 two-component system response regulator CreB -
EL066_RS20485 4294990..4295412 - 423 WP_126485007.1 protein YgfX Toxin
EL066_RS20490 4295393..4295659 - 267 WP_126485009.1 FAD assembly factor SdhE Antitoxin
EL066_RS20495 4295984..4296976 + 993 WP_126485011.1 tRNA-modifying protein YgfZ -
EL066_RS20500 4297062..4297739 - 678 WP_126485013.1 hemolysin III family protein -
EL066_RS20505 4297929..4298537 + 609 WP_126485015.1 HD domain-containing protein -
EL066_RS20510 4298579..4299514 - 936 WP_126485017.1 ribokinase -
EL066_RS20515 4299511..4300418 - 908 Protein_3964 allose kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16442.46 Da        Isoelectric Point: 10.4481

>T286875 WP_126485007.1 NZ_LR134151:c4295412-4294990 [Serratia plymuthica]
VAQWRCNVRISWRTQLLSLLTHGVLILLILIAPWPEGYGPIWLVMLTLVVFECIRSQKRIASLQGELRLLANKRLSWHGQ
EWLLVKQPWMPRYGILLTLQPIQGKKPRRLWLASDSMGKAEWRHLRQLLQYPSADDDEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10474.95 Da        Isoelectric Point: 5.6062

>AT286875 WP_126485009.1 NZ_LR134151:c4295659-4295393 [Serratia plymuthica]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDRLNDTDKALFIRLLESDDPDLFNWLMNHGAPQDSELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References