286872

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3919413..3920068 Replicon chromosome
Accession NZ_LR134151
Organism Serratia plymuthica strain NCTC8900

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL066_RS18735 Protein ID WP_126484530.1
Coordinates 3919413..3919802 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL066_RS18740 Protein ID WP_126484532.1
Coordinates 3919805..3920068 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL066_RS18720 3915889..3917322 + 1434 WP_164713344.1 MFS transporter -
EL066_RS18725 3917319..3918701 + 1383 WP_126484528.1 two-component system sensor histidine kinase BaeS -
EL066_RS18730 3918701..3919418 + 718 Protein_3621 two-component system response regulator BaeR -
EL066_RS18735 3919413..3919802 - 390 WP_126484530.1 type II toxin-antitoxin system VapC family toxin Toxin
EL066_RS18740 3919805..3920068 - 264 WP_126484532.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
EL066_RS18745 3920419..3920757 + 339 WP_126484534.1 YegP family protein -
EL066_RS18750 3921060..3922413 + 1354 Protein_3625 tRNA 5-hydroxyuridine modification protein YegQ -
EL066_RS18755 3922906..3923804 + 899 Protein_3626 lipid kinase YegS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-118)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14058.40 Da        Isoelectric Point: 7.8817

>T286872 WP_126484530.1 NZ_LR134151:c3919802-3919413 [Serratia plymuthica]
MYMFDTNTVSHLFRRHPGLLSAMEKVPPSTVCISSITEAELLFGVAKRQSKALKAMVTAFLAAVTVYDWDSEAARCYGVM
RASMEKKGKVLGALDQLIAAHALSRGATMVTSDRAFGMVPGLDVEDWTL

Download         Length: 390 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 10158.46 Da        Isoelectric Point: 4.8950

>AT286872 WP_126484532.1 NZ_LR134151:c3920068-3919805 [Serratia plymuthica]
MERIAKLFKNGRNQAVRLPVEFEFDTDRVYIRRDREGNVILSKYPAKPDSWEPLLNMIAKTPVPHDFLGADERQQGIADR
DPFAEEE

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References